PLoS ONE, 2022 Diabetic kidney disease (DKD) is heterogeneous in terms of proteinuria. Patients with DKD who present with low-grade proteinuria are more likely to have nephrosclerosis rather than traditional diabetic nephropathy. The amount of proteinuria might reflect
Satoshi Yamaguchi +7 more
doaj +3 more sources
Sirt6 deficiency exacerbates podocyte injury and proteinuria through targeting Notch signaling [PDF]
Nature Communications, 2017 Podocyte injury is a major determinant of proteinuric kidney disease and the identification of potential therapeutic targets for preventing podocyte injury has clinical importance.
Min Liu +15 more
semanticscholar +2 more sources
Significant proteinuria as a predictor of renal prognosis in malignant hypertension patients with thrombotic microangiopathy: a prospective cohort study [PDF]
BMC NephrologyBackground Malignant hypertension (mHTN) is the most severe form of hypertension. Thrombotic microangiopathy (TMA) serves as both a complication of mHTN and a contributor to its progression by exacerbating renal damage.
Wanxin Shi +10 more
doaj +2 more sources
Changes in proteinuria and the associated risks of ischemic heart disease, acute myocardial infarction, and angina pectoris in Korean population [PDF]
Epidemiology and Health, 2023 OBJECTIVES Proteinuria is widely used to predict cardiovascular risk. However, there is insufficient evidence to predict how changes in proteinuria may affect the incidence of cardiovascular disease.
Sung Keun Park +11 more
doaj +1 more source
New Ways of Thinking about Proteinuria and Progression of Renal Damage [PDF]
, 2010 Turner, Neil, Zhou, Y. S.
core +3 more sources
Terahertz spectra of proteinuria and non-proteinuria
Frontiers in Bioengineering and Biotechnology, 2023 In clinical practice, proteinuria detection is of great significance in the diagnosis of kidney diseases. Dipstick analysis is used in most outpatient settings to semi-quantitatively measure the urine protein concentration.
Zhenrui Xue +7 more
doaj +1 more source
Associations among Heavy Metals and Proteinuria and Chronic Kidney Disease
Diagnostics, 2021 Background: The prevalence of chronic kidney disease (CKD) is increasing annually in Taiwan. In addition to traditional risk factors, heavy metals contribute to the development of CKD.
H. Tsai +8 more
semanticscholar +1 more source
From Proteinuria to Fibrosis: An Update on Pathophysiology and Treatment Options
Kidney & Blood Pressure Research, 2021 Background: Proteinuria is a key biomarker in nephrology. It is central to diagnosis and risk assessment and the primary target of many important therapies.
Sonia Sharma, B. Smyth
semanticscholar +1 more source
Impact of lenvatinib-induced proteinuria and renal dysfunction in patients with thyroid cancer
Frontiers in Oncology, 2023 BackgroundProteinuria is the most frequent adverse event of lenvatinib use. However, the association between lenvatinib-induced proteinuria and renal dysfunction remains unclear.MethodsWe retrospectively reviewed medical records of patients with thyroid ...
Yuma Shibutani +12 more
doaj +1 more source
The Level of Urine Dipstick Proteinuria and Its Relation to the Risk of Incident Cholelithiasis
Journal of Epidemiology, 2021 Background: Previous studies have suggested the potential association between renal diseases and gallstone. The extent of proteinuria is recognized as a marker for the severity of chronic kidney disease.
Sung Keun Park +8 more
doaj +1 more source