Results 111 to 120 of about 187,783 (355)

Clinical utility and safety of finerenone in patients with heart failure: Rationale and design of FINE registry

ESC Heart Failure, EarlyView.
Abstract Aims Information about current use of finerenone in patients with heart failure (HF) finerenone in clinical practice is scarce, and its effectiveness in clinical practice in patients is scarce. We aim to assess both the baseline clinical profile and prognostic role of finerenone in patients with HF, irrespective of ejection fraction.
Gonzalo Luis Alonso Salinas, Amaia Martínez León, Diego Aguiar Cano, Alberto Esteban‐Fernández, José María Viéitez Flórez, Susana del Prado Díaz, Juan Górriz‐Magaña, Gregorio de Lara Delgado, Rafael González‐Manzanares, Pedro Caravaca‐Pérez, Francisco J. Pastor‐Pérez, Sandra Valdivieso‐Moré, Juan Quiles, Inés Ponz, Vanessa Escolar, Edison Omar Boada Lincango, Néstor Báez‐Ferrer, Gonzalo Gallego, Luis Almenar, Luis Gutiérrez de la Varga, Pau Codina, Alejandro Recio Mayoral, Aleix Fort, María Jesús Pinilla Lozano, David González‐Calle, Inés Gómez‐Otero, Cristina Salazar Mosteiro, Marta Cobo, Jesús Piqueras‐Flores, Clara Bonanad, Ana Huerta, Maria Ferré Vallverdú, Pablo Díez‐Villanueva   +32 more
wiley   +1 more source

Association of proteinuria with various clinical findings and morphologic variables of oxford classification in immunoglobulin a nephropathy patients

International Journal of Preventive Medicine, 2013
Background: Immunoglobulin A nephropathy (IgAN) with nephrotic syndrome is an uncommon form of IgAN. Clinical and morphological characteristics of proteinuria in IgAN, especially when is in nephrotic range have not yet been fully examined. This study was
Hamid Nasri, Yahya Madihi, Alireza Merrikhi, Allaleh Gheissari, Azar Baradaran, Soleiman Kheiri, Mahmoud Rafieian-Kopaei   +6 more
doaj  

Renal health after long-term exposure to tenofovir disoproxil fumarate (TDF) in HIV/HBV positive adults in Ghana [PDF]

, 2018
Objectives: The study assessed markers of renal health in HIV/HBV co-infected patients receiving TDF- containing antiretroviral therapy in Ghana. Methods: Urinary protein-to-creatinine ratio (uPCR) and albumin-to-protein ratio (uAPR) were measured ...
Appiah, L T, Beloukas, A, Chadwick, D, Geretti, A M, Phillips, R O, Post, F, Ruggiero, A, Sarfo, F S, Smith, C, Stockdale, A J, Villa, G   +10 more
core   +6 more sources

Proteinuria in IgA nephropathy

Kidney International, 1988
Clinicopathological data in 74 patients with IgA nephropathy were analyzed with special attention to level of proteinuria and its prognostic significance in this disease. Excretion rates exceeding 3 g per day (heavy), in the range of 1 to 2.9 g (moderate) and under 1 g per day (mild) each occurred in approximately equal proportions of patients.
Gloria Gallo, David S. Baldwin, Kotresha Neelakantappa   +2 more
openaire   +4 more sources

Canagliflozin reduces oral loop diuretic intensification in patients with type 2 diabetes: A participant‐level pooled analysis of the CANVAS and CREDENCE trials

European Journal of Heart Failure, EarlyView.
Among high‐risk patients with T2D, new oral loop diuretic intensification was frequent and portended adverse prognostic significance. Treatment with canagliflozin significantly reduced the need for loop diuretic intensification. ABSTRACT Aims The sodium–glucose cotransporter 2 inhibitor canagliflozin reduces the risk of heart failure (HF ...
Safia Chatur, Muthiah Vaduganathan, Robert A. Fletcher, Vlado Perkovic, Hiddo Heerspink, Clare Arnott, Carol Pollock, Kenneth W. Mahaffey, Bruce Neal, Meg Jardine, Scott D. Solomon, Brendon L. Neuen   +11 more
wiley   +1 more source

Use of Antihypertensive Agents and Association With Risk of Adverse Outcomes in Chronic Kidney Disease: Focus on Angiotensin-Converting Enzyme Inhibitors and Angiotensin Receptor Blockers. [PDF]

, 2018
Background Our objective was to determine patterns of antihypertensive agent use by stage of chronic kidney disease (CKD) and to evaluate the association between different classes of antihypertensive agents with nonrenal outcomes, especially in advanced ...
Johansen, Kirsten L, Ku, Elaine, Lin, Feng, McCulloch, Charles E, Vittinghoff, Eric   +4 more
core  

Kidney status and events preceding death in heart failure: A real‐world nationwide study

European Journal of Heart Failure, EarlyView.
Abstract Aims Chronic kidney disease is a frequent comorbidity in heart failure (HF) patients, affecting prognosis and mortality. This study investigates the relationship between kidney function and adverse kidney events preceding death in HF patients. Methods and results We analysed registry data of HF patients who died between 2014 and 2021, with at ...
Deewa Zahir Anjum, Caroline Hartwell Garred, Nicholas Carlson, Emil Fosbol, Mariam Elmegaard, Pardeep S. Jhund, John J.V. McMurray, Mark C. Petrie, Lars Kober, Morten Schou   +9 more
wiley   +1 more source

Impact of mineralocorticoid receptor antagonists on the risk of sudden cardiac death across cardio‐kidney‐metabolic diseases: A meta‐analysis of randomized clinical trials

European Journal of Heart Failure, EarlyView.
Abstract Aims Sudden cardiac death (SCD) is a prevalent cause of mortality among patients with cardio‐kidney‐metabolic (CKM) diseases. Mineralocorticoid receptor antagonists (MRAs) reduce the risk of SCD in patients with left ventricular dysfunction, but it is unclear if similar effects are expected across different CKM risk populations irrespective of
Pedro Marques, Faiez Zannad, João Pedro Ferreira   +2 more
wiley   +1 more source

IL-2 Therapy Diminishes Renal Inflammation and the Activity of Kidney-Infiltrating CD4+ T Cells in Murine Lupus Nephritis [PDF]

, 2019
An acquired deficiency of interleukin-2 (IL-2) and related disturbances in regulatory T cell (Treg) homeostasis play an important role in the pathogenesis of systemic lupus erythematosus (SLE).
Burmester, Gerd-Rüdiger, Enghard, Philipp, Humrich, Jens, Kloke, Lutz, Kühl, Anja, Riemekasten, Gabriela, Rose, Angelika, von Spee-Mayer, Caroline, Wu, Kaiyin   +8 more
core   +2 more sources

Apolipoprotein L1 gene variants associate with prevalent kidney but not prevalent cardiovascular disease in the Systolic Blood Pressure Intervention Trial. [PDF]

, 2015
Apolipoprotein L1 gene (APOL1) G1 and G2 coding variants are strongly associated with chronic kidney disease (CKD) in African Americans (AAs). Here APOL1 association was tested with baseline estimated glomerular filtration rate (eGFR), urine albumin ...
Bild, Diane E, Divers, Jasmin, Freedman, Barry I, Hawfield, Amret T, Kaysen, George A, Kimmel, Paul L, Langefeld, Carl D, Pajewski, Nicholas M, Raj, Dominic S, Reboussin, David M, Ricardo, Ana C, Rocco, Michael V, Sedor, John R, Systolic Blood Pressure Intervention Trial (SPRINT), Wright, Jackson T   +14 more
core   +1 more source