Results 51 to 60 of about 288,185 (387)

Effect of belimumab on proteinuria and anti-phospholipase A2 receptor autoantibody in primary membranous nephropathy

Nephrology, Dialysis and Transplantation, 2019
Background Immunosuppressant drugs reduce proteinuria and anti-phospholipase A2 receptor autoantibodies (PLA2R-Ab) in primary membranous nephropathy (PMN) with varying success and associated toxicities.
C. Barrett, L. Willcocks, R. Jones, R. Tarzi, R. B. Henderson, Gengqian Cai, Sophie Gisbert, Alexandra Belson, C. Savage   +8 more
semanticscholar   +1 more source

Membranoproliferative glomerulonephritis in patients with chronic venous catheters: a case report and literature review. [PDF]

, 2014
Chronic indwelling catheters have been reported to be associated with membranoproliferative glomerulonephritis (MPGN) via the activation of the classical complement pathway in association with bacterial infections such as coagulase negative ...
Nast, Cynthia C, Pham, Phuong-Chi T, Pham, Phuong-Thu T, Sy, John   +3 more
core   +2 more sources

Stage-specific action of matrix metalloproteinases influences progressive hereditary kidney disease. [PDF]

, 2006
BackgroundGlomerular basement membrane (GBM), a key component of the blood-filtration apparatus in the in the kidney, is formed through assembly of type IV collagen with laminins, nidogen, and sulfated proteoglycans.
Cosgrove, Dominic, Kalluri, Raghu, Khurana, Mona, Rao, Velidi H, Rougier, Jean-Philippe, Shield, Charles F, Werb, Zena, Werner, Michelle C, Zeisberg, Michael   +8 more
core   +3 more sources

Association of the clinicopathological characteristics and proteinuria remission of pediatric IgAV with nephrotic-range proteinuria: A retrospective cohort study

Frontiers in Pediatrics, 2022
BackgroundIgA vasculitis (IgAV) combined with nephrotic-range proteinuria is uncommon, and nephrotic-range proteinuria is considered a risk factor for poor prognosis in children with IgAV. There are few clinical studies with large samples.MethodsChildren
Zhijuan Kang, Zhijuan Kang, Mai Xun, Zhihui Li, Zuocheng Yang   +4 more
doaj   +1 more source

Protease-activated receptor 1 mediates thrombin-dependent, cell-mediated renal inflammation in crescentic glomerulonephritis. [PDF]

, 2000
Protease-activated receptor (PAR)-1 is a cellular receptor for thrombin that is activated after proteolytic cleavage. The contribution of PAR-1 to inflammatory cell-mediated renal injury was assessed in murine crescentic glomerulonephritis (GN).
Bernatowicz, Bohm, Bradford, Connolly, Cunningham, Erlich, Grandaliano, Holdsworth, Huang, Ishihara, Kahn, Li, Mari, Mueller, Naish, Neale, Nicholson, Nystedt, Rasmussen, Rydel, Shankar, Stone, Taylor, Taylor, Thomson, Tipping, Tipping, Tipping, Ueno, Vu, Vu, Woolkalis, Xu, Xu   +33 more
core   +3 more sources

Relationship between early proteinuria and long term outcome of kidney transplanted patients from different decades of donor age

BMC Nephrology, 2019
Background Proteinuria after kidney transplantation portends a worse graft survival. However the magnitude of proteinuria related to patient and graft survival and its correlation with donor and recipient characteristics are poorly explored. Methods This
Davide Diena, Maria Messina, Consuelo De Biase, Fabrizio Fop, Edoardo Scardino, Maura M. Rossetti, Antonella Barreca, Aldo Verri, Luigi Biancone   +8 more
doaj   +1 more source

Chewing areca nut as an independent risk factor for proteinuria in middle-aged men

Kaohsiung Journal of Medical Sciences, 2013
No previous large-scale research has reported the association of chewing areca nut (AN) with proteinuria. The aim of this study was to investigate such an association in men over a 7-year study.
Wen-Hsin Liu, Chih-Cheng Hsu, Yueh-Han Hsu   +2 more
doaj   +1 more source

Early Proteinuria Lowering by Angiotensin-Converting Enzyme Inhibition Predicts Renal Survival in Children with CKD.

Journal of the American Society of Nephrology, 2018
Background Although pharmacotherapeutic proteinuria lowering was found to be nephroprotective in adults, the predictive value of early drug-induced proteinuria reduction for long-term renal survival in pediatric CKD is unknown.
S. M. van den Belt, H. Heerspink, V. Gracchi, D. de Zeeuw, E. Wühl, F. Schaefer   +5 more
semanticscholar   +1 more source

SYHA1813, A VEGFR and CSF1R Inhibitor, in Patients With Recurrent High‐Grade Gliomas: A Multicenter, Open‐Label Phase I Study

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Recurrent high‐grade gliomas have a poor prognosis and limited therapeutic options. This study aimed to evaluate the safety and efficacy of SYHA1813, a dual inhibitor of VEGFR and CSF1R, in patients with recurrent high‐grade gliomas.
Zhuang Kang, Shenglan Li, Liang Wang, Qianxue Chen, Weiguo Hu, Ting Lei, Ying Mao, Jing Zhang, Xiaojun Xiang, Qiming Wang, Zhengwen He, Tao Sun, Yulei Wang, Mengqian Huang, Rong Zhang, Feng Chen, Wenbin Li   +16 more
wiley   +1 more source

Renal impairment in a rural African antiretroviral programme [PDF]

, 2009
Background: There is little knowledge regarding the prevalence and nature of renal impairment in African populations initiating antiretroviral treatment, nor evidence to inform the most cost effective methods of screening for renal impairment.
A Mocroft, A Reid, Ahmed Adam, Cara Franey, Deborah Knott, FA Post, Graham S Cooke, HE van Deventer, J Roe, JJ Bourgoignie, K Wools-Kaloustian, Marie-Louise Newell, Martin Dedicoat, MJ Siedner, MR Nelson, Richard J Lessells, SD Cohen, SK Gupta, T Barnighausen, TE Gerntholtz, Till Barnighausen, TK Rao, TM Han, WHO   +23 more
core   +3 more sources