Results 51 to 60 of about 175,007 (286)

A Comparative Analysis of the Ocular Microbiome: Insights into Healthy Eyes and Anophthalmic Sockets

Microorganisms
The purpose of this study is to characterize the ocular surface microbiota of patients with an anophthalmic cavity. An eNAT with 1 mL of Liquid Amies Medium was used to collect samples.
Francisco Zamorano-Martín, Guillermo Chumaceiro, Pablo Navarro-Torres, Davide Borroni, Facundo Urbinati, Ángel Molina, Andreu Paytuví-Gallart, Carlos Rocha-de-Lossada   +7 more
doaj   +1 more source

Functional Constraints on Replacing an Essential Gene with Its Ancient and Modern Homologs

mBio, 2017
Genes encoding proteins that carry out essential informational tasks in the cell, in particular where multiple interaction partners are involved, are less likely to be transferable to a foreign organism.
Betül Kacar, Eva Garmendia, Nurcan Tuncbag, Dan I. Andersson, Diarmaid Hughes   +4 more
doaj   +1 more source

Structure and evolution of chlorate reduction composite transposons. [PDF]

, 2013
UnlabelledThe genes for chlorate reduction in six bacterial strains were analyzed in order to gain insight into the metabolism. A newly isolated chlorate-reducing bacterium (Shewanella algae ACDC) and three previously isolated strains (Ideonella ...
Clark, Iain C, Coates, John D, Engelbrektson, Anna, Melnyk, Ryan A   +3 more
core   +2 more sources

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Early Microbes Modify Immune System Development and Metabolic Homeostasis—The “Restaurant” Hypothesis Revisited

Frontiers in Endocrinology, 2017
The developing infant gut microbiome affects metabolism, maturation of the gastrointestinal tract, immune system function, and brain development. Initial seeding of the neonatal microbiota occurs through maternal and environmental contact. Maternal diet,
Michael J. Nash, Daniel N. Frank, Jacob E. Friedman, Jacob E. Friedman   +3 more
doaj   +1 more source

ATP Is a Major Determinant of Phototrophic Bacterial Longevity in Growth Arrest

mBio, 2023
How bacteria transition into growth arrest as part of stationary phase has been well-studied, but our knowledge of features that help cells to stay alive in the following days and weeks is incomplete.
Liang Yin, Hongyu Ma, Elizabeth M. Fones, David R. Morris, Caroline S. Harwood   +4 more
doaj   +1 more source

Influence of Crohn’s disease related polymorphisms in innate immune function on ileal microbiome [PDF]

, 2019
We have previously identified NOD2 genotype and inflammatory bowel diseases (IBD) phenotype, as associated with shifts in the ileal microbiome (“dysbiosis”) in a patient cohort.
Ciorba, Matthew A, Davidson, Nicholas O, Frank, Daniel N, Gathungu, Grace, Li, Ellen, Nelson, Leah M, Robertson, Charles E, Sartor, R. Balfour, Shiekh, Shehzad S, Tian, Xinyu, Wang, Xuefeng, Wolber, Ashley, Zhang, Yuanhao, Zhu, Wei   +13 more
core   +3 more sources

Dispensabilities of Carbonic Anhydrase in Proteobacteria [PDF]

International Journal of Evolutionary Biology, 2012
Carbonic anhydrase (CA) (E.C. 4.2.1.1) is a ubiquitous enzyme catalysing interconversion between CO2 and bicarbonate. The irregular distribution of the phylogenetically distinct classes of CA in procaryotic genome suggests its complex evolutionary history in procaryotes.
Ueda, Kenji, Nishida, Hiromi, Beppu, Teruhiko   +2 more
openaire   +2 more sources

Medical Fabrics with Non‐Antibiotic, Supramolecular Antimicrobial Coatings: A Preventive Approach to Combat Biofilm Formation and Bacterial Dissemination

Advanced Healthcare Materials, EarlyView.
The study presents an antibiotic‐free strategy using medical fabrics coated with supramolecular assemblies of polyarginine and hyaluronic acid. These coatings showed strong antimicrobial and anti‐biofilm activity in vitro and in vivo, achieving major bacterial load reductions, including against MRSA.
Adjara Diarrassouba, Abdessalem Rekiki, Cécile Loubière, Sabine Kuchler‐Bopp, Lauriane Petit, Cynthia Calligaro, Derry Mercer, Aurore Gaudin, Naomi Canourgues, Emilie Adicéam, Benoit Beitz, Jeremy Welsch, Annabelle Vigué, Markus j. Kettel, Michael Karl, Chloé Guilbaud‐Chéreau, Philippe Lavalle, Nihal Engin Vrana, Skander Hathroubi   +18 more
wiley   +1 more source

A shared mucosal gut microbiota signature in primary sclerosing cholangitis before and after liver transplantation

Hepatology, EarlyView., 2022
In this study of the gut mucosal microbiota in primary sclerosing cholangitis (PSC), we found consistent microbiota features associated with PSC and recurrent PSC, PSC with inflammatory bowel disease and a persistent gut dysbiosis after liver transplantation Abstract Background and Aims Several characteristic features of the fecal microbiota have been ...
Mikal Jacob Hole, Kristin Kaasen Jørgensen, Kristian Holm, Peder R. Braadland, Malin Holm Meyer‐Myklestad, Asle Wilhelm Medhus, Dag Henrik Reikvam, Alexandra Götz, Krzysztof Grzyb, Kirsten Muri Boberg, Tom Hemming Karlsen, Martin Kummen, Johannes R. Hov   +12 more
wiley   +1 more source