Results 271 to 280 of about 13,195 (282)

Modulation of FLT3-ITD and CDK9 in acute myeloid leukaemia cells by novel proteolysis targeting chimera (PROTAC)

European Journal of Medicinal Chemistry, 2022
Eva Řezníčková, Sona Krajčovičová, Miroslav Perina   +2 more
exaly  

Discovery of BP3 as an efficacious proteolysis targeting chimera (PROTAC) degrader of HSP90 for treating breast cancer

European Journal of Medicinal Chemistry, 2022
Jingwen Liu, Jianhua Xu, Yang Liu
exaly  

Radiotherapy-Triggered Proteolysis Targeting Chimera Prodrug Activation in Tumors

Journal of the American Chemical Society, 2023
Yuchen Yang, Jinghong Li
exaly  

Induced protein degradation of anaplastic lymphoma kinase (ALK) by proteolysis targeting chimera (PROTAC)

Biochemical and Biophysical Research Communications, 2018
Chung Hyo Kang, Chi Hoon Park, Jong Yeon Hwang   +2 more
exaly  

Design and characterization of cereblon-mediated androgen receptor proteolysis-targeting chimeras

European Journal of Medicinal Chemistry, 2020
Seung-Hyun Jo, Sunjoo Ahn, Jeong-Hoon Kim   +2 more
exaly  

Proteolysis-targeting chimera (PROTAC) nanomedicines toward cancer treatment: From synthesis to therapeutic delivery

Biomaterials
Yilin Liu, Xiaoyuan Chen, Fuwu Zhang
exaly  

Discovery of a Potent Proteolysis Targeting Chimera Enables Targeting the Scaffolding Functions of FK506‐Binding Protein 51 (FKBP51)

Angewandte Chemie - International Edition
Thomas M Geiger, Michael Walz, Christian Meyners   +2 more
exaly  

AT1, a small molecular degrader of BRD4 based on proteolysis targeting chimera technology alleviates renal fibrosis and inflammation in diabetic nephropathy

Bioorganic Chemistry
Suzhen Wu
exaly  

Self‐Assembled Peptide‐Derived Proteolysis‐Targeting Chimera (PROTAC) Nanoparticles for Tumor‐Targeted and Durable PD‐L1 Degradation in Cancer Immunotherapy

Angewandte Chemie - International Edition
Jinseong Kim, Sukyung Song, Eun Hee Han   +2 more
exaly  

Design, synthesis, and biological characterization of proteolysis targeting chimera (PROTACs) for the ataxia telangiectasia and RAD3-related (ATR) kinase

European Journal of Medicinal Chemistry
Abdallah M Alfayomy, Ramy Ashry, Frank Erdmann   +2 more
exaly