Results 211 to 220 of about 823,777 (226)

Proteolysis targeting chimera (PROTAC) in drug discovery paradigm: Recent progress and future challenges

European Journal of Medicinal Chemistry, 2021
Liyan Cheng, Zhengrong Shen, Wenhai Huang   +2 more
exaly  

Modulation of FLT3-ITD and CDK9 in acute myeloid leukaemia cells by novel proteolysis targeting chimera (PROTAC)

European Journal of Medicinal Chemistry, 2022
Vladimír Kryštof, Miroslav Perina, Miroslav Soural   +2 more
exaly  

Novel Design Strategies to Enhance the Efficiency of Proteolysis Targeting Chimeras

ACS Pharmacology and Translational Science, 2022
Frank J Dekker
exaly  

Selective degradation of histone deacetylase 8 mediated by a proteolysis targeting chimera (PROTAC)†

Chemical Communications, 2022
Yukihiro Itoh, Makoto Oba, Yuri Takada
exaly  

Discovery of potent epidermal growth factor receptor (EGFR) degraders by proteolysis targeting chimera (PROTAC)

European Journal of Medicinal Chemistry, 2020
Minhang Xin, Hao Zhang, Hong-Yi Zhao
exaly  

Induced protein degradation of anaplastic lymphoma kinase (ALK) by proteolysis targeting chimera (PROTAC)

Biochemical and Biophysical Research Communications, 2018
Chi Hoon Park, Chung Hyo Kang, Jong Yeon Hwang   +2 more
exaly  

Proteolysis targeting chimera (PROTACS) as degraders of SMARCA2 and /or SMARCA4

2020
CIULLI ALESSIO, DANK CHRISTIAN, DIERS EMELYNE, FARNABY WILLIAM, ROY MICHAEL, STEURER STEFFEN, TRAINOR NICOLE   +6 more
openaire   +4 more sources

Proteolysis Targeting Chimeras (PROTACs): Emerging Therapeutics for Pancreatic Cancer

2022 International Conference on Biotechnology, Life Science and Medical Engineering (BLSME 2022), 2022
openaire   +1 more source

Self-Assembled Peptide-Derived Proteolysis-Targeting Chimera (PROTAC) Nanoparticles for Tumor-Targeted and Durable PD-L1 Degradation in Cancer Immunotherapy

Angewandte Chemie - International Edition
Joon Kyung Seong, Kwangmeyung Kim, Yongju Kim   +2 more
exaly  

PROTACS - Proteolysis Targeting Chimeras

openaire   +1 more source