Results 131 to 140 of about 183,121 (297)

Efficient glycosylation site utilization by intracellular apolipoprotein B: implications for proteasomal degradation

open access: yesJournal of Lipid Research, 1999
The balance between the hepatic assembly of apolipoprotein B (apoB) and its presecretory degradation at the level of the endoplasmic reticulum (ER) may control the secretion of apoB-containing lipoproteins.
Xue F. Huang, Gregory S. Shelness
doaj  

Advances in Single‐Cell Sequencing for Infectious Diseases: Progress and Perspectives

open access: yesAdvanced Science, EarlyView.
Single‐cell sequencing technologies uncover novel, unknown, and emergent features of many diseases. This review describes recent progress of single‐cell sequencing technologies and their applications in infectious diseases, summarizes the underlying commonalities of different infections and discusses future research directions, facilitating the ...
Mengyuan Lyu   +13 more
wiley   +1 more source

Editorial: Proteases of the prokaryotic cell envelope

open access: yesFrontiers in Microbiology, 2022
Rosana E. De Castro   +3 more
doaj   +1 more source

Focus on proteolysis

open access: yesThe Plant Cell
Nancy A Eckardt   +8 more
openaire   +2 more sources

Emodin Alleviates Sepsis‐Induced Multiorgan Damage by Inhibiting NETosis through Targeting Neutrophils BCL‐10

open access: yesAdvanced Science, EarlyView.
Emodin targets BCL‐10 to modulate the BCL‐10/MALT1 complex, thereby suppressing NF‐κB activation and significantly exerting multiorgan protective effects in sepsis. Abstract Sepsis is a life‐threatening condition caused by dysregulated host responses to infection, characterized by excessive inflammation and abnormal coagulation.
Xiaolong Xu   +16 more
wiley   +1 more source

Discovery of Natural Compound α‐Hederin via Large‐Scale Screening as a Targeted JAK/STAT3 Inhibitor for Ovarian Cancer Therapy

open access: yesAdvanced Science, EarlyView.
This study identifies α‐Hederin as a potent dual JAK1/JAK2 inhibitor that blocks STAT3 activation in ovarian cancer. By disrupting STAT3‐driven transcriptional programs, α‐Hederin suppresses tumor proliferation, invasion, and EMT, while enhancing cisplatin efficacy and overcoming chemoresistance.
Jiayu Wang   +9 more
wiley   +1 more source

Detection of low density lipoprotein particle fusion by proton nuclear magnetic resonance spectroscopy

open access: yesJournal of Lipid Research, 1998
Recent evidence suggests that fusion of low density lipoprotein (LDL) particles is a key process in the initial accumulation of lipid in the arterial intima.
Mika Ala-Korpela   +5 more
doaj  

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