Results 171 to 180 of about 183,121 (297)

The common yet enigmatic activity of histone tail clipping. [PDF]

J Biol Chem
Duncan EM.
europepmc   +1 more source

Comparison of the Proteolysis Produced by Rennet Extract and the Pepsin Preparation Metroclot during Ripening of Cheddar Cheese

, 1964
Nicholas Melachouris, S.L. Tuckey
openalex   +1 more source

Degradation of Abnormal Proteins in Escherichia coli: Relative Susceptibility of Canavanyl Proteins and Puromycin Peptides to Proteolysis in vitro [PDF]

, 1974
John T. Kemshead, Alan R. Hipkiss
openalex   +1 more source

Lipid Droplet‐Organized MDM2‐Mediated P53 Degradation: A Metabolic Switch Governing Diet‐Driven Tumor Progression

Advanced Science, EarlyView.
Tumor‐associated TP53 inactivation correlates with lipid droplet (LD) accumulation. High‐fat diets drive Cyb5r3‐Myh9‐mediated p53 enrichment on LD surfaces, accelerating its degradation while upregulating LD‐promoting factor CD36 expression to establish a feed‐forward loop. LD suppression or dietary intervention restores p53 and inhibits tumorigenesis,
Haiyang Liu, Lin Jing, Yixin Li, Jinxing Zhou, Xiaohui Cui, Sen Li, Shijie Yang, Fangming Kan, Junfeng Du, Wentao Zhong, Sheng Yu, Ning Wang, Xing Jia, Junhui Li, Pan Nie, Zhenzhong Chen, Ying Han, Lingxi Jiang, Xiyun Yan, Hongxia Duan, Baiyong Shen   +20 more
wiley   +1 more source

Calcium-dependent pathway as a primary cause of hypoxic RGC damage in monkey retinal explants. [PDF]

PLoS One
Nakajima E, Otsugu-Kobayashi M, Uchida T, Orihara K, Shearer TR, Azuma M.   +5 more
europepmc   +1 more source

Neutrophil Mobilization Triggers Microglial Functional Change to Exacerbate Cerebral Ischemia‐Reperfusion Injury

Advanced Science, EarlyView.
These study underscores the pivotal role of neutrophil‐derived myeloid‐related protein 14 (MRP14) in the pathophysiology of acute ischemic stroke (AIS). MRP14 not only disrupts mitochondrial function, thereby inhibiting microglial phagocytosis of neutrophils, but also activates microglial pyroptosis, exacerbating neuroinflammation following AIS ...
Huijuan Jin, Zhifang Li, Senwei Tan, Qinghui Xiao, Qingcan Li, Jiao Ye, Yifan Zhou, Yan Wan, Qiang Liu, Bijoy K Menon, Bo Hu   +10 more
wiley   +1 more source

Lon-dependent proteolysis in oxidative stress responses. [PDF]

J Bacteriol
Yigit K, Chien P.
europepmc   +1 more source

GASTRIC PROTEOLYSIS IN DISEASE: 4. PROTEINASE ACTIVITY OF EXTRACTS OF HUMAN GASTRIC ADENOCARCINOMATA

, 1960
W. H. Taylor
openalex   +1 more source

Removal of a large fragment of rhodopsin without changes in its spectral properties, by proteolysis of retinal rod outer segments [PDF]

, 1974
Paul Trayhurn, P. Mandel, N. Virmaux
openalex   +1 more source

HIGD1A Alleviates Oxidative Stress Related Ovarian Hypofunction by Enhancing Granulosa Cell Functions via NF‐κB/SOD2 Signaling Pathway

Advanced Science, EarlyView.
HIGD1A maintains redox homeostasis in granulosa cells by modulating SOD2‐mediated dismutation of superoxide into H2O2, which is cleared by CAT and GPX enzymes. However, reduced HIGD1A activates the NF‐κB pathway and upregulates SOD2, leading to intracellular H2O2 accumulation due to impaired clearance.
Huiying Li, Siying Cai, Hongbei Mu, Tianli Chang, Xiaofei Wang, Tianyu Tang, Tengyun Dong, Yu Zhang, Ling Zhang, Huaibiao Li, Liquan Zhou, Wenpei Xiang   +11 more
wiley   +1 more source