Results 261 to 270 of about 390,280 (339)

Small-molecule degron mimetics for targeted protein degradation. [PDF]

Essays Biochem
Liu X.
europepmc   +1 more source

CRISPR‐Cas9‐Loaded Theranostic Liposomes for Enhancing Radiosensitization of Prostate Cancer through POLD4 Gene Editing under Real‐Time MRI Monitoring

Advanced Science, EarlyView.
This study identifies POLD4 as a potential prostate cancer radiosensitization target through transcriptome sequencing. By encapsulating POLD4‐targeted CRISPR/Cas9 plasmids and USPIONs in cationic liposomes, an MRI‐monitored gene‐editing platform is established.
Xuhui Fan, Ruru Zhang, Linjun Yang, Shixiong Chen, Meijuan He, Yongqiang Wang, Linjie Huang, Jianfeng Zeng, Shuwang Wu, Mingyuan Gao, Han Wang   +10 more
wiley   +1 more source

Effect of polymerization by transglutaminase and proteolysis on the structure of 'Beta'-lactoglobulin and its antigenicity

, 2012
Villas Boas, Mariana Battaglin, 1981-
openalex   +1 more source

The Effect of Sodium Chloride on Proteolysis and on the Fate of Amino Acids Present in the Muscle of Codfish (Gadus callarias)

, 1959
E. Bilinski, Hélène Fougere
openalex   +1 more source

Cell‐Free DNA‐Based Theranostics for Inflammatory Disorders

Advanced Science, EarlyView.
Summary on the dual potential of cfDNA as biomarkers and therapeutic targets for inflammatory disorders. Figure was created with BioRender.com. ABSTRACT Inflammatory disorders are characterized by immune‐mediated inflammatory cascades that can affect multiple organs.
Jiatong Li, Yumei Wang, Xiaoxi Fan, Miao Xu, Jiawen Li, Wenfei Tan, Jianxiang Zhang, Heran Li   +7 more
wiley   +1 more source

Structural insights into scaffold-guided assembly of the Pseudomonas phage D3 capsid. [PDF]

Nat Commun
Belford AK, Maurer JB, Duda RL, Huet A, Conway JF.   +4 more
europepmc   +1 more source

Proteolysis in the maturation of avian retroviruses does not require calcium

, 1992
Volker M. Vogt, Haim Burstein, A M Skalka   +2 more
openalex   +1 more source

Bioorthogonal Sonodynamic Plug‐and‐Play Targeting Chimeras (SDPTAC) for Precise Targeted Protein Degradation

Advanced Science, EarlyView.
Bioorthogonal SDPTAC harnesses US‐responsive Ce6‐TCO and Tz ligands via IEDDA click chemistry to assemble degraders in situ, generating ROS that selectively eliminate nuclear, cytosolic, and membrane proteins, thereby suppressing deep‐seated tumors in vivo.
Yuhan Bao, Yaojin Zhu, Xinhao Wei, Yuxin Fang, Jiayi Zhu, Fei Gao, Guoqiang Dong, Shipeng He, Chunquan Sheng   +8 more
wiley   +1 more source

β-Catenin and AMPK/AKT/FOXO Signaling Mediate Doxorubicin-Induced Senescence and Lipid Accumulation in C2C12 Myoblasts. [PDF]

Biomol Ther (Seoul)
Yun C, Kim SH, Kwon D, Woo R, Chung KW, Lee J, Lee YH, Jung YS.   +7 more
europepmc   +1 more source