Results 281 to 290 of about 442,290 (346)

Enzymatic Tenderization of Garden Snail Meat (<i>Cornu aspersum aspersum</i>) Using Plant Cysteine Proteases. [PDF]

open access: yesMolecules
Tesarowicz I   +6 more
europepmc   +1 more source

A highly potent and broadly accessible bispecific nanobody for the treatment of ebola virus infections. [PDF]

open access: yesPLoS Pathog
Bu F   +9 more
europepmc   +1 more source

Above-Filter Digestion Proteomics Reveals Drug Targets and Localizes Ligand Binding Site. [PDF]

open access: yesJ Proteome Res
Sokolova B   +7 more
europepmc   +1 more source

Mitochondrial ClpP-Mediated Proteolysis Induces Selective Cancer Cell Lethality

open access: yesCancer Cell, 2019
The mitochondrial caseinolytic protease P (ClpP) plays a central role in mitochondrial protein quality control by degrading misfolded proteins. Using genetic and chemical approaches, we showed that hyperactivation of the protease selectively kills cancer
Jo Ishizawa, R Eric Davis, Ondrej Halgas
exaly   +2 more sources
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Unraveling the Role of Linker Design in Proteolysis Targeting Chimeras.

Journal of Medicinal Chemistry, 2021
A current bottleneck in the development of proteolysis targeting chimeras (PROTACs) is the empirical nature of linker length structure-activity relationships (SARs). A multidisciplinary approach to alleviate the bottleneck is detailed here.
Troy A Bemis, J. L. La Clair, M. Burkart
semanticscholar   +1 more source

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