Results 271 to 280 of about 183,121 (297)
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Trends in Genetics, 1999
Our present understanding of intracellular protein degradation developed from an attempt to understand the metabolic stability of proteins in cells. With the unravelling of its complex biochemical machinery has come a realization that protein degradation plays an important role in the most crucial events in the cell cycle, in signal transduction and in
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Our present understanding of intracellular protein degradation developed from an attempt to understand the metabolic stability of proteins in cells. With the unravelling of its complex biochemical machinery has come a realization that protein degradation plays an important role in the most crucial events in the cell cycle, in signal transduction and in
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1977
The presence of an enzyme associated with tropoelastin is described. The enzyme has a pH optimum between 7 and 9 and trypsin-like specificity. Upon incubation, tropoelastin (72,000 molecular weight) is cleaved into relatively high molecular weight fragments. In addition to the parent molecule, five discrete polypeptide bands are usually observed on SDS
Robert P. Mecham +2 more
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The presence of an enzyme associated with tropoelastin is described. The enzyme has a pH optimum between 7 and 9 and trypsin-like specificity. Upon incubation, tropoelastin (72,000 molecular weight) is cleaved into relatively high molecular weight fragments. In addition to the parent molecule, five discrete polypeptide bands are usually observed on SDS
Robert P. Mecham +2 more
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Proteolysis and lectin histochemistry
The Histochemical Journal, 1987Lectin binding to formalin-fixed, paraffin-embedded tissue can often be enhanced by pre-treatment of the sections with proteolytic enzymes. However, the pattern of staining may be profoundly influenced by the type of enzyme preparation which is used.
Jeffrey, I.J.M. +3 more
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Proteolysis in the rat lung: hypoxia and evidence for an inhibitor of proteolysis
American Journal of Physiology-Endocrinology and Metabolism, 1981We labeled proteins with [14C]phenylalanine in rats breathing air and assessed the rate of proteolysis in the isolated ventilated lung by measuring the accumulation of [14C]phenylalanine in the medium perfusing the lung. Ventilation with 0% O2 decreased the rate of proteolysis and the ATP content in the lung 60%.
F. Kishi +3 more
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Biochemical and Biophysical Research Communications, 1989
The calpain-induced proteolysis of tau associated with twice-cycled microtubules or from a total brain heat-stable fraction was studied. Twice-cycled microtubule tau was rapidly hydrolyzed by calpain. In contrast, tau purified from the total brain heat-stable fraction was very resistant to degradation by calpain.
Gail V.W. Johnson +2 more
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The calpain-induced proteolysis of tau associated with twice-cycled microtubules or from a total brain heat-stable fraction was studied. Twice-cycled microtubule tau was rapidly hydrolyzed by calpain. In contrast, tau purified from the total brain heat-stable fraction was very resistant to degradation by calpain.
Gail V.W. Johnson +2 more
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1982
Publisher Summary This chapter discusses the proteolysis of rhodopsin. Proteases have been valuable probes of the structure of many membrane proteins. Limited proteolysis of bovine rhodopsin has revealed information about the location of specific sites along the polypeptide sequence, about the organization of rhodopsin in natural and reconstituted ...
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Publisher Summary This chapter discusses the proteolysis of rhodopsin. Proteases have been valuable probes of the structure of many membrane proteins. Limited proteolysis of bovine rhodopsin has revealed information about the location of specific sites along the polypeptide sequence, about the organization of rhodopsin in natural and reconstituted ...
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Ozone and Pulmonary Proteolysis
Annals of Internal Medicine, 1970Excerpt To the editor: In their editorial on antitrypsin deficiency Falk and Briscoe (Ann Intern Med72:427-429, 1970) point out that intrapulmonary proteolysis might be due to either decreased inhi...
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Stimulation of proteolysis on calmodulin
Life Sciences, 1990The proteolysis of calmodulin by fungal protease (type XIX) was greatly enhanced in the presence of dGTP and MS2 RNA. Whereas, only moderate proteolytic activation on bacterial proteases (type XXVI) was observed in the presence of MS2 RNA. No appreciable proteolysis of calmodulin by bacterial protease (type IX) was observed.
Wu-Nan Kuo +5 more
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Proteolysis of fluoresceinated proteins
Molecular Immunology, 1965Abstract Pronase digestion of fluoresceinated BSA, fluroresceinated human and rabbit γ-globulin, and fluoresceinated BSA-rabbit anti-BSA precipitate was studied both as a function of time, and when digestion was complete, by separation of the products by gel fibration on Sephadex G-100.
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Proteolysis in Bacterial Sporulation
1980Publisher Summary Endospore formation and germination in various Bacillus species provide attractive experimental models for the study of cellular differentiation. These bacteria offer the advantages of easy cultivation and physiological manipulation, the possibility of genetic analysis, and a well-defined, relatively simple unicellular ...
Robert L. Switzer, Michael R. Maurizi
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