Results 261 to 270 of about 13,155 (273)

Induced protein degradation of histone deacetylases 3 (HDAC3) by proteolysis targeting chimera (PROTAC)

European Journal of Medicinal Chemistry, 2020
Fangyuan Cao, Deng Chen, Frank J Dekker
exaly  

Modulation of FLT3-ITD and CDK9 in acute myeloid leukaemia cells by novel proteolysis targeting chimera (PROTAC)

European Journal of Medicinal Chemistry, 2022
Eva Řezníčková, Sona Krajcovicova, Miroslav Peřina   +2 more
exaly  

Discovery of BP3 as an efficacious proteolysis targeting chimera (PROTAC) degrader of HSP90 for treating breast cancer

European Journal of Medicinal Chemistry, 2022
Jingwen Liu, Jianhua Xu, Yang Liu
exaly  

Radiotherapy-Triggered Proteolysis Targeting Chimera Prodrug Activation in Tumors

Journal of the American Chemical Society, 2023
Li Jinghong
exaly  

Induced protein degradation of anaplastic lymphoma kinase (ALK) by proteolysis targeting chimera (PROTAC)

Biochemical and Biophysical Research Communications, 2018
Chung Hyo Kang, Chi Hoon Park, Jong Yeon Hwang   +2 more
exaly  

Proteolysis targeting chimeras of Anaplastic lymphoma kinase

2020
Anaplastic lymphoma kinase (ALK)-positive Anaplastic Large Cell Lymphoma (ALCL) is a disease most commonly found in children and young adults (median age 34) with a slight male dominance. This cancer infects mainly lymph nodes, nevertheless it can be involved in other site than the lymph like the skin, soft tissues and bones.
openaire   +1 more source

Design and characterization of cereblon-mediated androgen receptor proteolysis-targeting chimeras

European Journal of Medicinal Chemistry, 2020
Seung-Hyun Jo, Sunjoo Ahn, Jeong-Hoon Kim   +2 more
exaly  

Proteolysis-targeting chimera (PROTAC) nanomedicines toward cancer treatment: From synthesis to therapeutic delivery

Biomaterials
Xiao Zhang, Xiaoyuan Chen, Fuwu Zhang
exaly  

Discovery of a Potent Proteolysis Targeting Chimera Enables Targeting the Scaffolding Functions of FK506‐Binding Protein 51 (FKBP51)

Angewandte Chemie - International Edition
Thomas Maximilian Geiger, Christian Meyners, Frederik Lermyte   +2 more
exaly  

Self‐Assembled Peptide‐Derived Proteolysis‐Targeting Chimera (PROTAC) Nanoparticles for Tumor‐Targeted and Durable PD‐L1 Degradation in Cancer Immunotherapy

Angewandte Chemie - International Edition
Joon-Kyung Seong, Kwangmeyung Kim
exaly