Results 171 to 180 of about 437,208 (323)
Proteome Analysis Database: online application of InterPro and CluSTr for the functional classification of proteins in whole genomes [PDF]
Rolf Apweiler
openalex +1 more source
Deciphering Cell Type Abundance in Proteomics Data Through Graph Neural Networks
GraphDEC constructs pseudo bulk reference data using a mixup strategy, then learns low dimensional representations via autoencoders to model intra and inter dataset relationships. These are processed through a multi view adaptive neighborhood aware GNN, integrating reference, target, and joint graphs.
Zhiming Dai+7 more
wiley +1 more source
In our study, we conducted circRNA expression profiling of Zhongwei goat skin exhibiting divergent curvature wool phenotypes at two developmental stages using the RNA‐seq. Functional verification assay demonstrated that circRNA8782 regulated fibroblast proliferation.
Yingxiao Su+9 more
wiley +1 more source
Alpha‐fetoprotein‐producing gastric cancer (AFPGC), a rare and aggressive subtype of gastric cancer, presents a high risk of liver metastasis. This study introduces the ANLiM score, a blood biomarker‐based predictive indicator for assessing liver metastasis and immunotherapy response.
Yongfeng Ding+26 more
wiley +1 more source
Ribonucleoprotein infrastructure regulating the flow of genetic information between the genome and the proteome [PDF]
Jack D. Keene
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The structure and assembly principles of a two‐component encapsulin nanocompartment shell are reported. The two‐component protein compartment self‐assembles from two distinct HK97‐fold shell proteins into a pseudo‐icosahedral protein shell with variable composition and irregular tiling.
Cassandra A. Dutcher+2 more
wiley +1 more source
HPD is identified as an RNA‐binding protein that promotes mRNA translation by binding to RRACH motifs via its double‐stranded RNA‐binding domains. This RNA‐binding activity critically sustains glycolysis in ovarian cancer cells. Disrupting HPD's RNA‐binding function effectively suppresses tumor growth and enhances therapeutic sensitivity, highlighting ...
Fei Xie+21 more
wiley +1 more source
The Dual Origin of the Yeast Mitochondrial Proteome
Olof Karlberg+3 more
openalex +1 more source