Results 231 to 240 of about 461,354 (348)

Distantly related bacteria share a rigid proteome allocation strategy with flexible enzyme kinetics. [PDF]

Proc Natl Acad Sci U S A
Zhu M, Mori M, Hwa T, Dai X.
europepmc   +1 more source

Mass-spectrometry-based draft of the Arabidopsis proteome

Nature, 2020
Julia Mergner, Martin Frejno, M. List, Michael Papacek, Xia Chen, Ajeet Chaudhary, Patroklos Samaras, Sandra Richter, Hiromasa Shikata, Maxim Messerer, D. Lang, Stefan Altmann, P. Cyprys, Daniel P. Zolg, Toby Mathieson, M. Bantscheff, R. Hazarika, Tobias Schmidt, C. Dawid, A. Dunkel, T. Hofmann, S. Sprunck, Pascal Falter-Braun, F. Johannes, Klaus F. X. Mayer, G. Jürgens, Mathias Wilhelm, J. Baumbach, E. Grill, K. Schneitz, C. Schwechheimer, B. Kuster   +31 more
semanticscholar   +1 more source

Redirecting the Peptide Cleavage Causes Protease Inactivation

Angewandte Chemie International Edition, Accepted Article.
Cysteine and serine proteases cleave peptides through covalent catalysis by generating a transient adduct with the N‐terminal part of the substrate after releasing its C‐terminal part. We demonstrate the unique redirection of this event leading to strong enzyme inactivation.
Michael Gütschow, Christian Breuer, Jim Küppers, Anna-Christina Schulz-Fincke, Anna Heilos, Carina Lemke, Petra Spiwokowá, Janina Schmitz, Laura Cremer, Marta Frigolé-Vivas, Michael Lülsdorff, Matthias D. Mertens, Filip Wichterle, Miloš Apeltauer, Martin Horn, Erik Gilberg, Norbert Furtmann, Jürgen Bajorath, Ulrike Bartz, Bernd Engels, Michael Mareš   +20 more
wiley   +1 more source

Gill Transcriptome, Proteome, and Histology in Female <i>Eriocheir sinensis</i> Under Copper Stress. [PDF]

Int J Mol Sci
Pan T, Li T, Yang M, Yu C, Jiang H, Ling J.   +5 more
europepmc   +1 more source

Small Molecule‐Induced Alterations of Protein Polyubiquitination Revealed by Mass‐Spectrometric Ubiquitome Analysis

Angewandte Chemie International Edition, Accepted Article.
Small molecules which alter protein ubiquitination are emerging as therapeutics due to their ability to modulate targets previously deemed undruggable. These compounds comprise PROTACs, molecular glue degraders and DUB inhibitors, among others. However, methods for the proteome‐wide monitoring of compound‐induced changes in protein polyubiquitination ...
Siska Führer, Kai Gallant, Farnusch Kaschani, Markus Kaiser, Petra Janning, Herbert Waldmann, Malte Gersch   +6 more
wiley   +1 more source

Simple In-Cell Processing Enables Deep Proteome Analysis of Low-Input <i>Caenorhabditis elegans</i>. [PDF]

Anal Chem
Elsayyid M, Tanis JE, Yu Y.
europepmc   +1 more source

Advancing plant metabolic research by using large language models to expand databases and extract labeled data

Applications in Plant Sciences, EarlyView.
Abstract Premise Recently, plant science has seen transformative advances in scalable data collection for sequence and chemical data. These large datasets, combined with machine learning, have demonstrated that conducting plant metabolic research on large scales yields remarkable insights.
Rachel Knapp, Braidon Johnson, Lucas Busta   +2 more
wiley   +1 more source

Offset Mass Carrier Proteome Improves Quantification of Multiplexed Single Cell Proteomics. [PDF]

Mol Cell Proteomics
Cheung TK, Zhu Y, Rose CM.
europepmc   +1 more source

Chromosome‐scale reference genome of Pectocarya recurvata, the species with the smallest reported genome size in Boraginaceae

Applications in Plant Sciences, EarlyView.
Abstract Premise Pectocarya recurvata (Boraginaceae, subfamily Cynoglossoideae), a species native to the Sonoran Desert (North America), has served as a model system for a suite of ecological and evolutionary studies. However, no reference genomes are currently available in Cynoglossoideae. A high‐quality reference genome for P.
Poppy C. Northing, Jessie A. Pelosi, D. Lawrence Venable, Katrina M. Dlugosch   +3 more
wiley   +1 more source

The catabolic nature of fermentative substrates influences proteomic rewiring in Escherichia coli under anoxic growth. [PDF]

Microb Cell Fact
Momin H, Appukuttan D, Venkatesh KV.
europepmc   +1 more source