Results 241 to 250 of about 538,471 (385)

Additional file 5: of Time-resolved transcriptome and proteome landscape of human regulatory T cell (Treg) differentiation reveals novel regulators of FOXP3

, 2018
Angelika Schmidt, Francesco Marabita, Narsis A. Kiani, Catharina C. Groß, Henrik J. Johansson, Szabolcs Éliás, Sini Rautio, Matilda Eriksson, Sunjay Fernandes, Gilad Silberberg, Ubaid Ullah, Urvashi Bhatia, Harri Lähdesmäki, Janne Lehtiö, David Gómez-Cabrero, Heinz Wiendl, Riitta Lahesmaa, Jesper Tegnér   +17 more
openalex   +1 more source

Amino Acid Frequency in the Proteome Is Not Associated With Realised Thermal Limit nor Dietary Niche Breadth in 35 Lepidoptera Species. [PDF]

Ecol Evol
Caron FS, Pietras Z, Eddine-Lomas A, von Hellfeld R, Morimoto J.   +4 more
europepmc   +1 more source

Spatio‐Temporal Proteomic Landscape Reveals Early Warning Signals of Esophageal Squamous Cell Carcinoma Progression

Advanced Science, EarlyView.
This study constructs a proteomic atlas of esophageal squamous cell carcinoma (ESCC) progression using esophageal biopsy samples. It identifies moderate dysplasia as the critical turning stage and a seven‐protein panel for early detection. Functionally, GBP6 loss promotes ESCC progression via cell cycle and epithelial‐mesenchymal transition (EMT ...
Xumiao Li, Jie Yuan, Min Gao, Jibin Liu, Qinqin Wang, Yaqi Zhang, Mingtao Cao, Xiaolin Hu, Hui Yang, Jun Li, Chen Li, Xiaoguang Li, Hui Wang   +12 more
wiley   +1 more source

Effects of arginine vasopressin on the urine proteome in rats

, 2016
Manxia An, Yanying Ni, Xundou Li, Youhe Gao   +3 more
openalex   +1 more source

Examining saliva proteomic dynamics in mitochondrial diseases from a perspective of intrinsic health. [PDF]

Sci Rep
Zhao J, Xu B, Huang T, Honfo SH, Trumpff C, Picard M, Cohen AA, Liu M.   +7 more
europepmc   +1 more source

Microcystin‐LR Triggers Renal Tubular Ferroptosis Through Epigenetic Repression of GPX4: Implications for Environmental Nephrotoxicity

Advanced Science, EarlyView.
MC‐LR stabilizes DNMT1/3a by blocking their ubiquitin‐mediated degradation, leading to Gpx4 promoter hypermethylation and E2F4/NCoR‐associated transcriptional repression, which drives renal tubular ferroptosis in mice. Pharmacological inhibition of DNA methylation (SGI‐1027) or ferroptosis (Fer‐1) disrupts this DNMT‐GPX4 axis, thereby alleviating MC‐LR‐
Shaoru Zhang, Qi Gao, Yi Peng, Huan Zhang, Qi Shen, Meihong Guo, Yuqing Gong, Lei Chu, Weidong Wu, Yanting Wen, Wangsen Cao, Yong Wang, Lihui Wang   +12 more
wiley   +1 more source

Integrated fibre-specific methylome and proteome profiling of human skeletal muscle across males and females with fibre-type deconvolution [PDF]

Andrew S. Palmer, Esther García-Domínguez, Megan F. Taylor, Andrew Garnham, Kirsten Seale, Joel R. Steele, Han-Chung Lee, Ralf B. Schittenhelm, Nir Eynon   +8 more
openalex   +1 more source

In-Depth Comparison of Reagent-Based Digestion Methods and Two Commercially Available Kits for Bottom-Up Proteomics

ACS Omega
Travis Uslan, Baiyi Quan, Ting-Yu Wang, Marion Pang, Yanping Qiu, Tsui-Fen Chou   +5 more
doaj   +1 more source

CoMPaseD: advanced planning of proteomic experiments aiming to identify small proteins. [PDF]

Microlife
Bartel J, Kaulich PT, Ferrero-Bordera B, Gelhausen R, Backofen R, Tholey A, Maaß S.   +6 more
europepmc   +1 more source

Targeting G3BP1 Condensate Topology Promotes Stress Granule Assembly via m6A‐IGF2BP1 for Ischemic Stroke Rescue

Advanced Science, EarlyView.
Our research reveals that small‐molecule icariin (ICA) directly binds Ras‐GTPase‐activating protein SH3 domain‐binding protein 1 (G3BP1), inducing conformational change and oligomerization. This interaction confers neuroprotection by recruiting insulin‐like growth factor 2 mRNA‐binding protein 1 (IGF2BP1) and modulating N6‐methyladenosine (m6A ...
Ling Li, Yong‐Dong Guo, Xiao‐Wen Zhang, Zhi‐Yong Du, Yu‐Qi Wang, Zhuo Yang, Qian‐Wei Luo, Fang‐Fang Zhuo, Tian‐Tian Wei, Zheng‐Ping Liu, Bo Han, Wei Yu, Pei‐Pei Zhang, Wei Zhou, Zhi‐Yuan Lu, Peng‐Fei Tu, Chun‐Hong Zheng, Ke‐Wu Zeng   +17 more
wiley   +1 more source