Results 241 to 250 of about 461,354 (348)

Proteome Birthdating: A Single-Sample Approach for Measuring Global Turnover Dynamics and "Protein Age". [PDF]

Bio Protoc
Meadow ME, Broas S, Hoare M, Ahmed M, Alimohammadi F, Welle KA, Swovick K, Hryhorenko JR, Jain A, Martinez JC, Seluanov A, Gorbunova V, Buchwalter A, Ghaemmaghami S.   +13 more
europepmc   +1 more source

Proteomic Profiling of the Large‐Vessel Vasculitis Spectrum Identifying Shared Signatures of Innate Immune Activation and Stromal Remodeling

Arthritis &Rheumatology, EarlyView.
Objective Takayasu arteritis (TAK) and giant cell arteritis (GCA), the most common forms of large‐vessel vasculitis (LVV), can result in serious morbidity. Understanding the molecular basis of LVV should aid in developing better biomarkers and treatments. Methods Plasma proteomic profiling of 184 proteins was performed in two cohorts. Cohort 1 included
Robert T. Maughan, Erin Macdonald‐Dunlop, Lubna Haroon‐Rashid, Louise Sorensen, Natalie Chaddock, Shauna Masters, Andrew Porter, Marta Peverelli, Charis Pericleous, Andrew Hutchings, James Robinson, Taryn Youngstein, Raashid A. Luqmani, Justin C. Mason, Ann W. Morgan, James E. Peters   +15 more
wiley   +1 more source

Towards a kingdom of reproductive life - the core sperm proteome. [PDF]

Reproduction
Pini T, Nixon B, Karr TL, Teperino R, Sanz-Moreno A, da Silva-Buttkus P, Tüttelmann F, Kliesch S, Gailus-Durner V, Fuchs H, Marschall S, Hrabě de Angelis M, Skerrett-Byrne DA.   +12 more
europepmc   +1 more source

Genome‐Wide Aggregated Trans Effects Analysis Identifies Genes Encoding Immune Checkpoints as Core Genes for Rheumatoid Arthritis

Arthritis &Rheumatology, EarlyView.
Objective The sparse effector “omnigenic” hypothesis postulates that the polygenic effects of common single nucleotide polymorphisms (SNPs) on a typical complex trait are mediated by trans effects that coalesce on expression of a relatively sparse set of core genes.
Athina Spiliopoulou, Andrii Iakovliev, Darren Plant, Megan Sutcliffe, Seema Sharma, Cankut Cubuk, Myles Lewis, Costantino Pitzalis, Anne Barton, Paul M. McKeigue   +9 more
wiley   +1 more source

Model of metabolism and gene expression predicts proteome allocation in Pseudomonas putida. [PDF]

NPJ Syst Biol Appl
Tibocha-Bonilla JD, Gandhi V, Lieng C, Moyne O, Santibáñez-Palominos R, Zengler K.   +5 more
europepmc   +1 more source

Peripheral blood gene expression profiling shows prognostic significance for the course of interstitial lung disease in systemic sclerosis

Arthritis &Rheumatology, Accepted Article.
Objective We used data from the placebo arm of the SENSCIS trial to determine the prognostic/predictive significance of peripheral blood cell (PBC) transcript modules for the course of forced vital capacity (FVC) in patients with systemic sclerosis‐associated interstitial lung disease (SSc‐ILD) with and without mycophenolate mofetil (MMF) treatment ...
Shervin Assassi, Christopher P. Denton, Matthias Zwick, Ramona Schmid, Carina Ittrich, Tobias Litzenburger, Sudha Visvanathan   +6 more
wiley   +1 more source

A transcriptomic and proteomic analysis and comparison of human brain tissue from patients with and without epilepsy. [PDF]

Sci Rep
Zhu T, Zhou Y, Zhang L, Kong L, Tang H, Xiao Q, Sun X, Shen F, Zhou H, Ni W, Liu S, Gao H, Jin G, Jia X, Hua F.   +14 more
europepmc   +1 more source

Clinical proteomics [PDF]

Osteoarthritis and Cartilage, 2013
openaire   +2 more sources

Variability in intestinal drug metabolizing enzymes and transporters in Crohn's disease and potential impact on oral drug absorption

British Journal of Clinical Pharmacology, EarlyView.
Aims The aim of study was to generate quantitative data on the abundance of drug‐metabolizing enzymes and transporters (DMETs) in inflamed and non‐inflamed Crohn's disease (CD) ileum and colon, for incorporation into physiologically based pharmacokinetic (PBPK) models, enabling prediction of oral drugs' pharmacokinetics (PK) perturbation in CD patients.
Sarah Alrubia, Brahim Achour, Zubida M. Al‐Majdoub, Amin Rostami‐Hodjegan, Jill Barber   +4 more
wiley   +1 more source

Investigating the Effects of <i>Arabidopsis thaliana</i> Cruciferin Double Knockouts on Amino Acid Profiles, Dry Seed Proteome, and Oxidative Stress Levels. [PDF]

MicroPubl Biol
Bagaza C, Ansaf H, Yobi A, Angelovici R.
europepmc   +1 more source