Results 271 to 280 of about 538,471 (385)

A Human Protein-Protein Interaction Network: A Resource for Annotating the Proteome

Cell, 2005
U. Stelzl, Uwe Worm, M. Lalowski, Christian Haenig, F. Brembeck, H. Goehler, Martin Stroedicke, Martina Zenkner, Anke Schoenherr, Susanne Koeppen, Jan Timm, Sascha Mintzlaff, C. Abraham, Nicole Bock, Silvia Kietzmann, A. Goedde, Engin Toksöz, A. Droege, S. Krobitsch, B. Korn, W. Birchmeier, H. Lehrach, E. Wanker   +22 more
semanticscholar   +1 more source

Neuroprotective Nanoplatform Integrating Antioxidant MXene Nanozymes and Ferroptosis Inhibitors for Targeted Therapy of Cerebral Ischemia‐Reperfusion Injury

Advanced Science, EarlyView.
Cerebral ischemia‐reperfusion injury (CIRI) is a key pathological process limiting the efficacy of stroke therapy. This study has developed an innovative, multifunctional, brain‐targeted nanoplatform (RFP) containing MXene nanoenzymes and ferroptosis inhibitors.
Lu Wang, Chao Hou, Shuo Li, Lizhi Yang, Yiqun Lin, Sen Wang, Xiaohua Jia, Hui Hui, Wen He, Wei Zhang   +9 more
wiley   +1 more source

Temporal Dynamics of the Milk Proteome in Women with Gestational Diabetes Mellitus. [PDF]

J Proteome Res
Mu Q, Luo Y, Li W, Guo Y, Zeng X, Li J, Zhu L, Xing Y, Zhu J.   +8 more
europepmc   +1 more source

Acetylation Regulates ACSL4 Degradation Through Chaperone‐Mediated Autophagy to Alleviate Intervertebral Disc Degeneration

Advanced Science, EarlyView.
Intervertebral disc degeneration is triggered by ACSL4 accumulation‐mediated ferroptosis of nucleus pulposus cells due to CMA dysfunction. KAT2B promotes ACSL4 degradation via CMA through acetylation. AAV‐mediated LAMP2A delivery or engineered exosomes rescue nucleus pulposus cell senescence and disc degeneration.
Zhouwei Wu, Zhichen Jiang, Chenglong Hong, Shu Yang, Shuqing Jin, Chenyu Wu, Kaijie Guo, Jiang Liu, Shaobo Xu, Chenggui Wang, Xiangyang Wang   +10 more
wiley   +1 more source

Transcriptome and proteome analyses of proteases in biotroph fungal pathogen Cladosporium fulvum

, 2019
Mansoor Karimi Jashni, Ate van der Burgt, Evy Battaglia, Rahim Mehrabi, Jérôme Collemare, P.J.G.M. de Wit   +5 more
openalex   +2 more sources

TOGR3, a Proteasome β4 Subunit, Orchestrates Sugar Homeostasis to Trade Off Growth and Thermotolerance in Rice

Advanced Science, EarlyView.
This study identifies a novel thermoregulatory mechanism in rice: TOGR3 partners with 26S proteasome subunits, including TT1, to drive thermoresponsive ubiquitin–proteasome activity, maintaining sugar homeostasis in stomatal regulation to balance growth and stress resistance.
Biyao Zhang, Xiaoyan Wu, Ting Xu, Feifei Guo, Xiaolu Shen, Cuiping Meng, Yanan Wang, Xue Han, Hong Zhao, Yongbiao Xue   +9 more
wiley   +1 more source

Proteome-wide microarray-based screening of PAR-binding proteins

Bong Gu Kang, Sung-Ung Kang, Jae Jin Kim, Ji-Sun Kwon, Jean-Philippe Gagné, Seo Yun Lee, Soyeon Kim, Karl S Lee, Shinwon Ha, Jun Seop Jeong, Yun-Il Lee, Heng Zhu, Dongsan Kim, Guy G. Poirier, Ho Chul Kang, Valina L. Dawson, Ted M. Dawson   +16 more
openalex   +1 more source

Epigenome–proteome integration in aged skeletal muscle after exercise training [PDF]

Adam P. Sharples
openalex   +1 more source

Cytoplasmic fluidity and the cold life: proteome stability is decoupled from viability in psychrophiles. [PDF]

Nat Commun
Caviglia B, Timr S, Guiral M, Giudici-Orticoni MT, Seydel T, Beck C, Peters J, Sterpone F, Paciaroni A.   +8 more
europepmc   +1 more source

Mechanism‐Driven Screening of Membrane‐Targeting and Pore‐Forming Antimicrobial Peptides

Advanced Science, EarlyView.
To combat antibiotic resistance, this study employs mechanism‐driven screening with machine learning to identify pore‐forming antimicrobial peptides from amphibian and human metaproteomes. Seven peptides are validated, showing minimal toxicity and membrane disruption.
Jiaxuan Li, Chenguang Yang, Ruihan Dong, Juan Francisco Bada Juarez, Lei Wang, Maximilian Emanuel Wettstein, Dali Wang, Chan Cao, Ying Lu, Chen Song   +9 more
wiley   +1 more source