Results 271 to 280 of about 205,179 (309)

Methodological Aspects of μLC-MS/MS for Wide-Scale Proteomic Analysis of Anthracycline-Induced Cardiomyopathy. [PDF]

ACS Omega
Kupčík R, Lenčová O, Mazurová Y, Štěrba M, Vajrychová M.   +4 more
europepmc   +1 more source

TRiC Is a Structural Component of Mammalian Sperm Axonemes

Cytoskeleton, EarlyView.
ABSTRACT The TRiC chaperonin is responsible for folding ~5%–10% of the proteome in eukaryotic cells. Our recent cryo‐electron microscopy studies of axonemes from diverse mammalian cell types led to the surprising discovery that a fully assembled TRiC chaperonin is a structural component of mammalian sperm flagella, where it is tethered to the radial ...
Alan Brown, Miguel Ricardo Leung, Tzviya Zeev‐Ben‐Mordehai, Rui Zhang   +3 more
wiley   +1 more source

The nonlinear cysteine redox dynamics in the i-space: A proteoform-centric theory of redox regulation. [PDF]

Redox Biol
Cobley JN, Chatzinikolaou PN, Schmidt CA.   +2 more
europepmc   +1 more source

Nondegradative Synthetic Molecular Glues Enter the Clinic

ChemMedChem, EarlyView.
Proximity‐inducing drugs are a novel therapeutic modality and currently mainly focused on target degradation. Recently, nondegradative molecular glues, inspired by natural products that reprogram cyclophilin A (Cyp A) to inhibit K‐Ras, have entered the clinic.
Maximilian L. Repity, Robin C. E. Deutscher, Felix Hausch   +2 more
wiley   +1 more source

Serum Proteomics of Experimental Malaria-Associated ARDS Reveals a Regulation of Acute-Phase Response Proteins. [PDF]

J Immunol Res
Rosa-Fernandes L, Santiago VF, da Silva-Santos Y, Lopes TT, Peixoto EPM, Rodrigues SAM, Marinho CRF, Palmisano G, Epiphanio S.   +8 more
europepmc   +1 more source

Detection of circulating tumor cells is achieved by flow cytometry in melanoma patients

Cytometry Part B: Clinical Cytometry, EarlyView.
Abstract Melanoma is an aggressive skin tumor whose incidence is rising sharply, and for which the determination of new prognostic factors is a major challenge. In oncology, circulating tumor cells (CTCs) are at the heart of much research, as they represent a source of tumor material obtained non‐invasively by liquid biopsy.
Ludivine Fourdrain, Théo Brochet, Valentin Clichet, Guillaume Chaby, Brigitte Gubler, Loïc Garçon, Jean‐Philippe Arnault, Thomas Boyer   +7 more
wiley   +1 more source

Evolutionary sparse learning reveals the shared genetic basis of convergent traits. [PDF]

Nat Commun
Allard JB, Sharma S, Patel R, Sanderford M, Tamura K, Vucetic S, Gerhard GS, Kumar S.   +7 more
europepmc   +1 more source

Mediterranean vs. Western diet effects on the primate cerebral cortical pre-synaptic proteome: Relationships with the transcriptome and multi-system phenotypes. [PDF]

Alzheimers Dement
Berson E, Frye BM, Gajera CR, Saarunya G, Perna A, Phongpreecha T, Shome S, Negrey JD, Aghaeepour N, Montine TJ, Craft S, Register TC, Shively CA.   +12 more
europepmc   +1 more source

Exoproteomic Evidence for BcTSPO-Mediated Regulation of Virulence Factors in Bacillus cereus. [PDF]

Proteomics
Duport C, Armengaud J.
europepmc   +1 more source

Pro‐adrenomedullin as an independent predictive biomarker for heart failure in atrial fibrillation and flutter

ESC Heart Failure, EarlyView.
Abstract Aims This study aimed to investigate potential biomarkers for predicting incident heart failure (HF) in patients with atrial fibrillation and flutter (AF and AFL), utilizing proteomic data from the UK Biobank Pharma Proteomics Project (UKB‐PPP).
Gaifeng Hu, Xiaodong Peng, Liu He, Yiwei Lai, Nian Liu, Xin Li, Caihua Sang, Jianzeng Dong, Changsheng Ma   +8 more
wiley   +1 more source