Results 291 to 300 of about 538,471 (385)

Alphaviral Capsid Proteins Inhibit Stress Granule Assembly via Competitive RNA Binding With G3BP1

open access: yesAdvanced Science, EarlyView.
Stress granules exert antiviral functions. This study illustrates a conserved function of alphaviral capsid proteins in modulating stress granules. Oligomerization mediated by a helical motif coupled with a positively charged intrinsically disordered region (IDR) directly competes with G3BP1 for RNA binding, thereby disrupting G3BP1‐RNA liquid–liquid ...
Yun Zhang   +10 more
wiley   +1 more source

Mapping the dynamic RNA binding proteome in human effector T cells identifies differentiation and cytotoxicity regulators

open access: gold
M. Valeria Lattanzio   +10 more
openalex   +1 more source

OCTN2 Activates a Non‐Canonical Carnitine Metabolic Pathway to Promote MASH‐HCC Progression and Immunotherapy Resistance

open access: yesAdvanced Science, EarlyView.
In non‐MASH‐HCC, L‐carnitine promotes tumor progression primarily through its classical role in enhancing fatty acid oxidation (FAO). However, in MASH‐HCC, where FAO is markedly suppressed, L‐carnitine shifts from this canonical function to serve instead as an intracellular acetyl group buffer.
Chuqi Xia   +11 more
wiley   +1 more source

Comparison of proteome functions in seminal plasma and spermatozoa of Murrah buffalo bulls: (A) Molecular functions, (B) Biological processes, (C) Cellular components.

open access: green
Hikmayani Iskandar (22478027)   +13 more
openalex   +1 more source

Proteomic profiling reveals age-related changes in transporter proteins in the human blood-brain barrier. [PDF]

open access: yesSci Rep
Zhou X   +10 more
europepmc   +1 more source

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