Results 301 to 310 of about 461,354 (348)

An Analysis of Intrinsic Protein Disorder in Antimicrobial Peptides. [PDF]

Protein J
Antonietti M, Kim CK, Granack S, Hadzijahic N, Taylor Gonzalez DJ, Herskowitz WR, Uversky VN, Djulbegovic MB.   +7 more
europepmc   +1 more source

Cardioprotective effects of semaglutide on isolated human ventricular myocardium

European Journal of Heart Failure, EarlyView.
Semaglutide reduces late sodium current (INa) and diastolic calcium (Ca) sparks in human cardiomyocytes from aortic stenosis (AS) and end‐stage heart failure with reduced ejection fraction (HFrEF) patients, thereby increasing Ca transients. Improved Ca storage may underly the enhanced contractility of human cardiomyocytes upon semaglutide.
Thomas Krammer, Maria J. Baier, Philipp Hegner, Tilman Zschiedrich, David Lukas, Matthias Wolf, Christian Le Phu, Vanessa Lutz, Katja Evert, Kostiantyn Kozakov, Jing Li, Andreas Holzamer, Lars S. Maier, Zdenek Provaznik, Donald M. Bers, Stefan Wagner, Julian Mustroph   +16 more
wiley   +1 more source

RBC-GEM: A genome-scale metabolic model for systems biology of the human red blood cell. [PDF]

PLoS Comput Biol
Haiman ZB, Key A, D'Alessandro A, Palsson BO.   +3 more
europepmc   +1 more source

Clinical and plasma proteomic characterization of heart failure with supranormal left ventricular ejection fraction: An emerging entity of heart failure

European Journal of Heart Failure, EarlyView.
Heart failure (HF) with supranormal ejection fraction (HFsnEF) is an unnoticed but emerging entity in HF. This study showed that HFsnEF carries a similarly increased cardiovascular risk as HF with reduced ejection fraction (HFrEF) and distinct structural and proteomic characteristics from HFrEF, warranting a further comprehensive understanding and ...
Yasuhiko Sakata, Kotaro Nochioka, Satoshi Yasuda, Koichi Ishida, Takashi Shiroto, Jun Takahashi, Shintaro Kasahara, Ruri Abe, Shinsuke Yamanaka, Takahide Fujihashi, Hideka Hayashi, Shintaro Kato, Katsunori Horii, Kanako Teramoto, Tsutomu Tomita, Satoshi Miyata, Koichiro Sugimura, Iwao Waga, Masao Nagasaki, Hiroaki Shimokawa   +19 more
wiley   +1 more source

A spatio-temporal transcriptomic and proteomic dataset of developing Brassica napus seeds. [PDF]

Sci Data
Knoch D, Rugen N, Thiel J, Heuermann MC, Kuhlmann M, Rizzo P, Meyer RC, Wagner S, Schippers JHM, Braun HP, Altmann T.   +10 more
europepmc   +1 more source

Severity of effect considerations regarding the use of mutation as a toxicological endpoint for risk assessment: A report from the 8th International Workshop on Genotoxicity Testing (IWGT)

Environmental and Molecular Mutagenesis, EarlyView.
Abstract Exposure levels without appreciable human health risk may be determined by dividing a point of departure on a dose–response curve (e.g., benchmark dose) by a composite adjustment factor (AF). An “effect severity” AF (ESAF) is employed in some regulatory contexts.
Barbara L. Parsons, Marc A. Beal, Kerry L. Dearfield, George R. Douglas, Min Gi, B. Bhaskar Gollapudi, Robert H. Heflich, Katsuyoshi Horibata, Michelle Kenyon, Alexandra S. Long, David P. Lovell, Anthony M. Lynch, Meagan B. Myers, Stefan Pfuhler, Alisa Vespa, Andreas Zeller, George E. Johnson, Paul A. White   +17 more
wiley   +1 more source

Proteomic insights into the environmental adaptation of the subtropical brain coral host <i>Platygyra carnosa</i>. [PDF]

iScience
Ma H, Dellisanti W, Hao Chung JT, Pan Y, Liu G, Wu J, Qiu JW, Chan LL, Zhang L.   +8 more
europepmc   +1 more source

Temporal proteome profiling of Botrytis cinerea reveals proteins involved in plant invasion and survival. [PDF]

Sci Rep
Singh S, Hegde M, Kaur I, Adlakha N.
europepmc   +1 more source

Transcriptomic and Proteomic Profiling of Rabbit Kidney Cells Infected with Equine Herpesvirus 8. [PDF]

Viruses
Ji Y, Xu D, Si W, Zhang Y, Khan MZ, Zhao X, Liu W.   +6 more
europepmc   +1 more source

<i>Ehrlichia chaffeensis</i> proteomic profiling reveals distinct expression patterns of infectious and replicating forms. [PDF]

Front Cell Infect Microbiol
Kondethimmanahalli C, Ganta RR.
europepmc   +1 more source