Results 351 to 360 of about 538,471 (385)
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Journal of Proteomics, 2011
Seeds comprise a protective covering, a small embryonic plant, and a nutrient-storage organ. Seeds are protein-rich, and have been the subject of many mass spectrometry-based analyses. Seed storage proteins (SSP), which are transient depots for reduced nitrogen, have been studied for decades by cell biologists, and many of the complicated aspects of ...
Ján A, Miernyk, Martin, Hajduch
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Seeds comprise a protective covering, a small embryonic plant, and a nutrient-storage organ. Seeds are protein-rich, and have been the subject of many mass spectrometry-based analyses. Seed storage proteins (SSP), which are transient depots for reduced nitrogen, have been studied for decades by cell biologists, and many of the complicated aspects of ...
Ján A, Miernyk, Martin, Hajduch
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2011
Proteomics has significantly contributed to improve our understanding of cell structures and functions in the last decade. The possibility to identify large sets of proteins from minute amount of material, linked with the isolation of cellular organelles using various cell fractionation methods, has provided unique insights into the molecular ...
Sophie, Duclos, Michel, Desjardins
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Proteomics has significantly contributed to improve our understanding of cell structures and functions in the last decade. The possibility to identify large sets of proteins from minute amount of material, linked with the isolation of cellular organelles using various cell fractionation methods, has provided unique insights into the molecular ...
Sophie, Duclos, Michel, Desjardins
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Mass Spectrometry Reviews, 2012
AbstractActivity‐based proteomics (ABP) employs small molecular probes to specifically label sets of enzymes based on their shared catalytic mechanism. Given that the vast majority of lipases belong to the family of serine hydrolases and share a nucleophilic active‐site serine as part of a catalytic triad, activity‐based probes are ideal tools to study
Matthias, Schittmayer +1 more
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AbstractActivity‐based proteomics (ABP) employs small molecular probes to specifically label sets of enzymes based on their shared catalytic mechanism. Given that the vast majority of lipases belong to the family of serine hydrolases and share a nucleophilic active‐site serine as part of a catalytic triad, activity‐based probes are ideal tools to study
Matthias, Schittmayer +1 more
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2007
Proteomics has been widely applied to several biomedical fields in recent years. The high-throughput capability of proteomics allows simultaneous examination of numerous proteins and offers the possibility of a global analysis of proteins in cells, tissues or biofluids.
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Proteomics has been widely applied to several biomedical fields in recent years. The high-throughput capability of proteomics allows simultaneous examination of numerous proteins and offers the possibility of a global analysis of proteins in cells, tissues or biofluids.
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2009
The proteome of the cell is at the frontier of being too complex for proteomic analysis. Organelles provide a step up. Organelles compartmentalize the cell enabling a proteome, physiology and metabolism analysis in time and in space. Protein complexes separated by electrophoresis have been identified as the next natural level to characterize the ...
Matthias, Plöscher +4 more
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The proteome of the cell is at the frontier of being too complex for proteomic analysis. Organelles provide a step up. Organelles compartmentalize the cell enabling a proteome, physiology and metabolism analysis in time and in space. Protein complexes separated by electrophoresis have been identified as the next natural level to characterize the ...
Matthias, Plöscher +4 more
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Mass Spectrometry Reviews, 2003
Abstract I. Introduction: The Need for a Repertoire of Proteome Analysis Strategies as the Analytical Complement 28 II. Rationale of Proteome Analysis at the Level of Subcellular Structures 29 III. Analytical Tools in Subcellular Proteomics 29 A.
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Abstract I. Introduction: The Need for a Repertoire of Proteome Analysis Strategies as the Analytical Complement 28 II. Rationale of Proteome Analysis at the Level of Subcellular Structures 29 III. Analytical Tools in Subcellular Proteomics 29 A.
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2014
Proteome provides highly valuable information on the amount, modifications, and subcellular localization of polypeptides. Accordingly, geneticists, molecular biologists, and biochemists have logically applied these new tools to respond to different lines of biological questions (inventory of proteins, impact of a mutation, dynamics of protein ...
Pascal, Cosette, Thierry, Jouenne
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Proteome provides highly valuable information on the amount, modifications, and subcellular localization of polypeptides. Accordingly, geneticists, molecular biologists, and biochemists have logically applied these new tools to respond to different lines of biological questions (inventory of proteins, impact of a mutation, dynamics of protein ...
Pascal, Cosette, Thierry, Jouenne
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Molecular Biology, 2002
On the basis of recent fundamentally novel developments in the protein structure a proteomic code is suggested, that would potentially allow to describe sequence, structure, and function of proteins by a spectrum of elementary loop-n-lock units. All major characteristics of the nearly standard units are described, and first five "codons" of the ...
E N, Trifonov, I N, Berezovsky
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On the basis of recent fundamentally novel developments in the protein structure a proteomic code is suggested, that would potentially allow to describe sequence, structure, and function of proteins by a spectrum of elementary loop-n-lock units. All major characteristics of the nearly standard units are described, and first five "codons" of the ...
E N, Trifonov, I N, Berezovsky
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2009
Proteomic profiling of subcellular compartments has many advantages over traditional proteomic approaches using whole cell lysates as it allows for detailed proteome analysis of a specific organelle and corresponding functional characteristics. The microsome is a critical, membranous compartment involved in the synthesis, sorting, and secretion of ...
Diana M, Wong, Khosrow, Adeli
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Proteomic profiling of subcellular compartments has many advantages over traditional proteomic approaches using whole cell lysates as it allows for detailed proteome analysis of a specific organelle and corresponding functional characteristics. The microsome is a critical, membranous compartment involved in the synthesis, sorting, and secretion of ...
Diana M, Wong, Khosrow, Adeli
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