Results 61 to 70 of about 591,485 (302)

Cerrena unicolor Laccases, Genes Expression and Regulation of Activity

open access: yesBiomolecules, 2021
A white rot fungus Cerrena unicolor has been identified as an important source of laccase, unfortunately regulation of this enzyme genes expression is poorly understood.
Anna Pawlik   +10 more
doaj   +1 more source

An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes

open access: yesFEBS Letters, EarlyView.
GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg   +14 more
wiley   +1 more source

A proteomic investigation of Fusobacterium nucleatum alkaline-induced biofilms [PDF]

open access: yes, 2012
Background: The Gram negative anaerobe Fusobacterium nucleatum has been implicated in the aetiology of periodontal diseases. Although frequently isolated from healthy dental plaque, its numbers and proportion increase in plaque associated with disease ...
Neville J Gully   +11 more
core   +1 more source

Isolation of Stem Cells of the Degenerated Lumbar Intervertebral Disc Using a Low Cost and Very Effective Technique

open access: yesGlobal Spine Journal, 2014
Introduction The limitations of regenerative therapy of the tissue using stem cells are, among others, the length of time until a satisfactory amount of viable cells is obtained for the therapy and the high financial cost.
A. Falavigna   +5 more
doaj   +1 more source

Transcriptomic and proteomic analysis of Oenococcus oeni adaptation to wine stress conditions

open access: yesFrontiers in Microbiology, 2016
Oenococcus oeni, the main lactic acid bacteria responsible for malolactic fermentation in wine, has to adapt to stressful conditions, such as low pH and high ethanol content. In this study, the changes in the transcriptome and the proteome of O. oeni PSU-
Mar Margalef-Català   +4 more
doaj   +1 more source

Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics

open access: yesFEBS Letters, EarlyView.
Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt   +8 more
wiley   +1 more source

Research Progress on Regulatory Mechanisms of Conical Cell Morphogenesis in Arabidopsis thaliana

open access: yesPlants
Flowering plants are universally adorned with conical epidermal cells on their petals, which play a pivotal role in their function. They modulate the petal microenvironment by regulating wetting and temperature homeostasis and enhance pollinator ...
Xinfei Li, Deshu Lin, Lilan Zhu
doaj   +1 more source

Web Tool for Navigating and Plotting SomaLogic ADAT Files

open access: yesJournal of Open Research Software, 2017
SOMAscan™ is a complex proteomic platform created by SomaLogic. Experimental data resulting from the assay is provided by SomaLogic in a proprietary text-based format called ADAT.
Foo Cheung   +7 more
doaj   +1 more source

A comparison of proteomic, genomic, and osteological methods of archaeological sex estimation

open access: yesScientific Reports, 2020
Sex estimation of skeletons is fundamental to many archaeological studies. Currently, three approaches are available to estimate sex–osteology, genomics, or proteomics, but little is known about the relative reliability of these methods in applied ...
Tammy Buonasera   +16 more
semanticscholar   +1 more source

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

open access: yesFEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang   +2 more
wiley   +1 more source

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