Results 51 to 60 of about 591,485 (302)

Proteomic Changes Associated With Sperm Fertilizing Ability in Meat-Type Roosters

Frontiers in Cell and Developmental Biology, 2021
The molecular basis of male fertility remains unclear, especially in chickens, where decades of genetic selection increased male fertility variability as a side effect.
Anaïs Vitorino Carvalho, Laura Soler, Aurore Thélie, Isabelle Grasseau, Luiz Cordeiro, Daniel Tomas, Daniel Tomas, Daniel Tomas, Ana-Paula Teixeira-Gomes, Ana-Paula Teixeira-Gomes, Valérie Labas, Valérie Labas, Valérie Labas, Elisabeth Blesblois   +13 more
doaj   +1 more source

The human gut microbiome across the life course

FEBS Letters, EarlyView.
Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero, Basak Bahcivanci, Antonietta Hayhoe, Animesh Acharjee, Ezgi Özkurt   +4 more
wiley   +1 more source

The H3ABioNet helpdesk: an online bioinformatics resource, enhancing Africa’s capacity for genomics research

BMC Bioinformatics, 2019
Background Currently, formal mechanisms for bioinformatics support are limited. The H3Africa Bioinformatics Network has implemented a public and freely available Helpdesk (HD), which provides generic bioinformatics support to researchers through an ...
Judit Kumuthini, Lyndon Zass, Sumir Panji, Samson P. Salifu, Jonathan K. Kayondo, Victoria Nembaware, Mamana Mbiyavanga, Ajayi Olabode, Ali Kishk, Gordon Wells, Nicola J. Mulder, as members of the Sustainability and Outreach Work Package of the H3ABioNet Consortium   +11 more
doaj   +1 more source

Omics analysis in nutrition science

Mexican Journal of Medical Research ICSA, 2022
The prevalence of diseases affecting human health related to the environment and inadequate nutrition is high. Strategies that seek to mitigate them have focused on lifestyle changes and healthy nutrition focusing on general guidelines that do not ...
Wendoline Anaya Morua
doaj   +1 more source

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

FEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

Proteomic candidate biomarkers of drug-induced nephrotoxicity in the rat [PDF]

, 2012
Improved biomarkers of acute nephrotoxicity are coveted by the drug development industry, regulatory agencies, and clinicians. In an effort to identify such biomarkers, urinary peptide profiles of rats treated with two different nephrotoxins were ...
Hanig, J., Mischak, H., Harald Mischak (103627), Rouse Rodney, Mullen, W., Metzger, J., William Mullen (103621), Rodney Rouse, William Mullen, Jochen Metzger, Jochen Metzger (171762), Hanig Joseph, Siwy, J., Joseph Hanig, Justyna Siwy (103595), Mullen William, Harald Mischak, Rouse, R., Justyna Siwy, Rodney Rouse (171753), Metzger Jochen, Joseph Hanig (82484), Siwy Justyna, Mischak Harald   +23 more
core   +2 more sources

Overloading And unpacKing (OAK) - droplet-based combinatorial indexing for ultra-high throughput single-cell multiomic profiling

Nature Communications
Multiomic profiling of single cells by sequencing is a powerful technique for investigating cellular diversity. Existing droplet-based microfluidic methods produce many cell-free droplets, underutilizing bead barcodes and reagents. Combinatorial indexing
Bing Wu, Hayley M. Bennett, Xin Ye, Akshayalakshmi Sridhar, Celine Eidenschenk, Christine Everett, Evgeniya V. Nazarova, Hsu-Hsin Chen, Ivana K. Kim, Margaret Deangelis, Leah A. Owen, Cynthia Chen, Julia Lau, Minyi Shi, Jessica M. Lund, Ana Xavier-Magalhães, Neha Patel, Yuxin Liang, Zora Modrusan, Spyros Darmanis   +19 more
doaj   +1 more source

Engineering of Microbial Expression Systems for the In Vitro Production of Anticancer Peptides

Proceedings
Introduction: Cancer causes nearly 10 million deaths worldwide each year, with approximately 704,000 new cases in Brazil [...]
Giovana A. Vasconcelos, Pedro E. B. Guedes, Thais M. M. Ferreira, Victor A. Cunha, André R. C. Junior, Octavio L. Franco, Karen O. Osiro   +6 more
doaj   +1 more source

Design and analysis strategies for robust microbiome ageing research

FEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik, İsmail Güderer, Yi Wang, Tayyaba Alvi, Prasoon Pandey, Handan Melike Dönertaş   +5 more
wiley   +1 more source

ABL kinase‐dependent phosphorylation of SH proteins promotes their direct interaction with CRK family SH2 domains

FEBS Letters, EarlyView.
CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens, Brendan W. Chandler, Anna M. Schmoker, Jaye L. Weinert, Charlotte A. Kearns, Warren T. Yacawych, Amila Šemić, Alicia M. Ebert, Bryan A. Ballif   +8 more
wiley   +1 more source