Results 161 to 170 of about 784,733 (395)

Revisiting biomarker discovery by plasma proteomics

Molecular Systems Biology, 2017
Clinical analysis of blood is the most widespread diagnostic procedure in medicine, and blood biomarkers are used to categorize patients and to support treatment decisions.
Philipp E. Geyer, L. Holdt, D. Teupser, M. Mann   +3 more
semanticscholar   +1 more source

Proteomics [PDF]

Journal of Biomedicine and Biotechnology, 2010
Garcia, Benjamin A., Cooper, Helen J., Dorrestein, Pieter C., Tang, Kai, Ueberheide, Beatrix M.   +4 more
openaire   +2 more sources

Beyond digital twins: the role of foundation models in enhancing the interpretability of multiomics modalities in precision medicine

FEBS Open Bio, EarlyView.
This review highlights how foundation models enhance predictive healthcare by integrating advanced digital twin modeling with multiomics and biomedical data. This approach supports disease management, risk assessment, and personalized medicine, with the goal of optimizing health outcomes through adaptive, interpretable digital simulations, accessible ...
Sakhaa Alsaedi, Xin Gao, Takashi Gojobori   +2 more
wiley   +1 more source

How do our cells build their protein interactome?

Nature Communications, 2018
Chaperones are cellular factors that help in the folding of newly synthesized polypeptides (or clients) and, in some cases, ensure their integration within larger complexes.
Benoit Coulombe, Philippe Cloutier, Marie-Soleil Gauthier   +2 more
doaj   +1 more source

Proteomics: Technologies and Their Applications.

Journal of Chromatographic Science, 2017
Proteomics involves the applications of technologies for the identification and quantification of overall proteins present content of a cell, tissue or an organism.
B. Aslam, M. Basit, M. A. Nisar, M. Khurshid, M. Rasool   +4 more
semanticscholar   +1 more source

The cysteine proteome

Free Radical Biology and Medicine, 2015
The cysteine (Cys) proteome is a major component of the adaptive interface between the genome and the exposome. The thiol moiety of Cys undergoes a range of biologic modifications enabling biological switching of structure and reactivity. These biological modifications include sulfenylation and disulfide formation, formation of higher oxidation states,
Joshua D. Chandler, Dean P. Jones, Young-Mi Go   +2 more
openaire   +3 more sources

Towards a proteomics meta-classification [PDF]

, 2004
that can serve as a foundation for more refined ontologies in the field of proteomics. Standard data sources classify proteins in terms of just one or two specific aspects.
Kumar, Anand, Smith, Barry
core   +1 more source

Advanced glycation end products promote the release of endothelial cell‐derived mitocytosis

FEBS Open Bio, EarlyView.
Under diabetic conditions, AGEs induce mitochondrial damage in HUVECs, activating migrasome‐mediated mitocytosis. Migrasomes encapsulate damaged mitochondria and are released into the extracellular space, facilitating intercellular mitochondrial transfer.
Rong Liu, Yuhao Zhang, Tiantian Ge, Hao Wu, Yongbin Ma, Honghua Ye, Fei Guo   +6 more
wiley   +1 more source

Proteomics and Its Current Application in Biomedical Area: Concise Review

The Scientific World Journal
Biomedical researchers tirelessly seek cutting-edge technologies to advance disease diagnosis, drug discovery, and therapeutic interventions, all aimed at enhancing human and animal well-being.
Semira Gobena, Bemrew Admassu, Mebrie Zemene Kinde, Abebe Tesfaye Gessese   +3 more
doaj   +1 more source

In-depth proteomics identifies a role for autophagy in controlling reactive oxygen species mediated endothelial permeability [PDF]

, 2016
Endothelial cells (ECs) form the inner layer of blood vessels and physically separate the blood from the surrounding tissue. To support tissues with nutrients and oxygen, the endothelial monolayer is semipermeable.
Anderson, Kurt I., Athineos, Dimitris, Blyth, Karen, Erami Rud Majani, Zahra, Neilson, Lisa, Patella, Francesca, Ryan, Kevin, Zanivan, Sara Rossana   +7 more
core   +10 more sources