Results 171 to 180 of about 521,206 (335)
New Drug Discovery in the Postgenomic Era: From Genomics to Proteomics
Stephen M. Stahl
openalex +2 more sources
Objective Lupus nephritis (LN) management remains challenging, and novel noninvasive biomarkers are needed. This study quantified serum soluble mediators in the Accelerating Medicines Partnership (AMP) LN cohort to identify biomarkers of histological features and treatment response.
Andrea Fava +26 more
wiley +1 more source
β‐Catenin/c‐Myc Axis Modulates Autophagy Response to Different Ammonia Concentrations
Ammonia, detoxified by the liver into urea and glutamine, impacts autophagy differently at varying levels. Low ammonia activates autophagy via c‐Myc and β‐catenin, while high levels suppress it. Using Huh7 cells and Spf‐ash mice, c‐Myc's role in cytoprotective autophagy is revealed, offering insights into hyperammonemia and potential therapeutic ...
S. Sergio +11 more
wiley +1 more source
Ultra-fast proteomics with Scanning SWATH
Christoph B. Messner +18 more
semanticscholar +1 more source
A Spatially Resolved View on the Aging Substantia nigra: An Exploratory Proteomic Study
Although aging is the most important risk factor for several neurodegenerative diseases, the molecular effects of physiological aging are still understudied. By applying spatially‐resolved proteomic analyses of the human substantia nigra pars compacta, alterations in vesicular trafficking and mitochondrial proteins are observed, as well as reduced ...
Britta Eggers +10 more
wiley +1 more source
Proteomics technology: Character references [PDF]
Potter Wickware, Paul Smaglik
openalex +1 more source
Quantitative Proteomics of the Cancer Cell Line Encyclopedia
David P. Nusinow +20 more
semanticscholar +1 more source
The fabrication of a cellularized, multilayered 3D printed cylindrical model comprising hybrid bioinks inspired by the natural extracellular environment as an approach to artery mimetics, is presented. Using embedded bioprinting, interlayer crosslinking of self‐supporting concentric cylinders is achieved.
Uxue Aizarna‐Lopetegui +7 more
wiley +1 more source
Functional proteomics: large-scale analysis of protein kinase activity. [PDF]
David S. Lawrence
openalex +1 more source

