Results 281 to 290 of about 490,947 (358)

Proteomic method identifies proteins nitrated in vivo during inflammatory challenge

, 2001
Kulwant S. Aulak, Masaru Miyagi, Yan Lin, Karen A. West, Duna Massillon, John W. Crabb, Dennis J. Stuehr   +6 more
openalex   +1 more source

Mannose‐Glycated Metal‐Phenolic Microcapsules Orchestrate Phenotype Switch of Macrophages for Boosting Tumor Immunotherapy

Advanced Science, EarlyView.
Immunomodulatory metal‐phenolic microcapsules (mMPMs) is developed in this study that leverages dopamine‐modified hyaluronic acid and FeIII assemble on mannose‐glycated bovine serum albumin microbubbles. mMPMs effectively promote macrophage internalization and M1 polarization, enhancing pro‐inflammatory responses.
Xin Tan, Renwang Sheng, Weikun Li, Yinghua Tao, Zonghao Liu, Ning Yang, Syeda Safia Hashmi, Feiling Feng, Fangzhou Liu, Liqin Ge   +9 more
wiley   +1 more source

Advances in multi-omics studies of microvascular invasion in hepatocellular carcinoma. [PDF]

Eur J Med Res
Wang L, Xu HX, Wang R, Zhang F, Deng D, Zhu X, Tan Q, Yang H.   +7 more
europepmc   +1 more source

Development of MDM2‐Targeting PROTAC for Advancing Bone Regeneration

Advanced Science, EarlyView.
This work presents a creative pipeline for developing MDM2‐targeting PROTACs (MDM2‐PROTACs) for application in bone regeneration. The developed PROTACs (CL144 and CL174) are validated for their degradation efficiency and osteogenic effects in human BMSCs.
Sol Jeong, Jae‐Kook Cha, Wasim Ahmed, Jaewan Kim, Minsup Kim, Kyung Tae Hong, Wonji Choi, Sunjoo Choi, Tae Hyeon Yoo, Hyun‑Ju An, Seung Chan An, Jaemin Lee, Jimin Choi, Sun‐Young Kim, Jun‐Seok Lee, Soonchul Lee, Junwon Choi, Jin Man Kim   +17 more
wiley   +1 more source

Algorithms and tools for data-driven omics integration to achieve multilayer biological insights: a narrative review. [PDF]

J Transl Med
Morabito A, De Simone G, Pastorelli R, Brunelli L, Ferrario M.   +4 more
europepmc   +1 more source

A Novel Theranostic Strategy for Malignant Pulmonary Nodules by Targeted CECAM6 with 89Zr/131I‐Labeled Tinurilimab

Advanced Science, EarlyView.
This study investigates the integrated diagnostic and therapeutic strategy utilizing 89Zr/131I‐labeled tinurilimab for the management of malignant lung nodules, with a particular focus on lung adenocarcinoma (LUAD). CEACAM6, which is highly expressed in most LUAD patients, activates the Src/FAK signaling pathway, thereby promoting cell proliferation ...
Chongyang Chen, Keying Zhu, Jing Wang, Donghui Pan, Xinyu Wang, Yuping Xu, Junjie Yan, Lizhen Wang, Min Yang   +8 more
wiley   +1 more source

Salivary Proteome Insights: Evaluation of Saliva Preparation Methods in Mucopolysaccharidoses Research. [PDF]

Biomedicines
Soporan MA, Pralea IE, Iacobescu M, Moldovan RC, Alkhzouz C, Miclea D, Iuga CA.   +6 more
europepmc   +1 more source

A mini-review: Proteomic analysis, a post-genomic approach

, 2000
Jean-François Chich
openalex   +1 more source

Nuclear envelope proteomics: Novel integral membrane proteins of the inner nuclear membrane

, 2001
Mathias Dreger, Luiza Bengtsson, Torsten Schöneberg, Henning Otto, Ferdinand Hucho   +4 more
openalex   +1 more source

Asprosin‐FABP5 Interaction Modulates Mitochondrial Fatty Acid Oxidation through PPARα Contributing to MASLD Development

Advanced Science, EarlyView.
Aided by FABP5, abnormally elevated asprosin in hepatocytes enters the nucleus, targets and inhibits PPARα binding to the CPT1A promoter, thereby suppressing FAO. Circulating asprosin exacerbates insulin resistance, collectively driving MASLD progression.
Yuan‐Yuan Yu, Min Feng, Yi Chen, Hong‐Lin Jia, Qi Zhang, Ming Tong, Yan‐Xi Li, Yu Zhao, Xin‐Xin Liu, Shi‐Feng Cao, Zheng‐kai Wang, Hou‐wei Li, Xue Liu, Yan Zhang   +13 more
wiley   +1 more source