Results 311 to 320 of about 507,435 (334)
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2013
Today we have the genome sequences for humans as well as many other animals, plants, fungi, and bacteria. All these data have given scientists a global view of the various genes in humans and others. However, genes are only the first step to understanding how an organism works. Genes are transcribed into mRNA and then translated into protein.
David P. Clark, Nanette J. Pazdernik
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Today we have the genome sequences for humans as well as many other animals, plants, fungi, and bacteria. All these data have given scientists a global view of the various genes in humans and others. However, genes are only the first step to understanding how an organism works. Genes are transcribed into mRNA and then translated into protein.
David P. Clark, Nanette J. Pazdernik
openaire +3 more sources
Espert Review of Proteomics, 2022
Introduction Biological fluids are routine samples for diagnostic testing and monitoring. Blood samples are typically measured because of their moderate invasive collection and high information content on health and disease.
L. Dayon, Ornella Cominetti, M. Affolter
semanticscholar +1 more source
Introduction Biological fluids are routine samples for diagnostic testing and monitoring. Blood samples are typically measured because of their moderate invasive collection and high information content on health and disease.
L. Dayon, Ornella Cominetti, M. Affolter
semanticscholar +1 more source
Proteomics, 2020
This review provides a brief overview of the development of data‐independent acquisition (DIA) mass spectrometry‐based proteomics and selected DIA data analysis tools.
Fangfei Zhang +4 more
semanticscholar +1 more source
This review provides a brief overview of the development of data‐independent acquisition (DIA) mass spectrometry‐based proteomics and selected DIA data analysis tools.
Fangfei Zhang +4 more
semanticscholar +1 more source
Journal of Nephrology, 2012
Proteome analysis has emerged as a new field of protein science offering the possibility of achieving unbiased identification, quantification and functional assessment of all proteins and peptides present in biological samples. Proteomics technologies are being used with increased frequency in the renal community.
BONOMINI, Mario +3 more
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Proteome analysis has emerged as a new field of protein science offering the possibility of achieving unbiased identification, quantification and functional assessment of all proteins and peptides present in biological samples. Proteomics technologies are being used with increased frequency in the renal community.
BONOMINI, Mario +3 more
openaire +5 more sources
Journal of Proteomics, 2011
We believe that this JoP special issue on Redox Proteomics not only represents one of the numerous attempts to start a network of information among multiplelaboratories working on this delicate topic, but it also promises to start bridging the persisting gaps between the clinical and the academic milieu, hopping that, for the foreseeable future, this ...
Scaloni A, Zolla L
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We believe that this JoP special issue on Redox Proteomics not only represents one of the numerous attempts to start a network of information among multiplelaboratories working on this delicate topic, but it also promises to start bridging the persisting gaps between the clinical and the academic milieu, hopping that, for the foreseeable future, this ...
Scaloni A, Zolla L
openaire +5 more sources
Analytical Chemistry, 2003
Proteomics is critically dependent on optimal sample preparation. Particularly, the interface between protein digestion and mass spectrometric analysis has a large influence on the overall quality and sensitivity of the analysis. We here describe a novel
J. Rappsilber, Y. Ishihama, M. Mann
semanticscholar +1 more source
Proteomics is critically dependent on optimal sample preparation. Particularly, the interface between protein digestion and mass spectrometric analysis has a large influence on the overall quality and sensitivity of the analysis. We here describe a novel
J. Rappsilber, Y. Ishihama, M. Mann
semanticscholar +1 more source
Biomolecular Engineering, 2001
Several genome sequencing projects have recently been completed and the majority of human coding regions have been sequenced. In the next step many of the further studies will concentrate on proteins. Proteomics methods are essential for studying protein expression, activity, regulation and modifications.
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Several genome sequencing projects have recently been completed and the majority of human coding regions have been sequenced. In the next step many of the further studies will concentrate on proteins. Proteomics methods are essential for studying protein expression, activity, regulation and modifications.
openaire +3 more sources
Proteomics and Functional Proteomics
2010The study of the protein complement of the genome (or proteome), including the characterization of proteins derived from the genetic code to the comparison of variations in their expression patterns and levels under different conditions, study of their interactions, and identification of their functional role in the context of health and disease, is ...
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Proteomics methods for subcellular proteome analysis
The FEBS Journal, 2013The elucidation of the subcellular distribution of proteins under different conditions is a major challenge in cell biology. This challenge is further complicated by the multicompartmental and dynamic nature of protein localization. To address this issue, quantitative proteomics workflows have been developed to reliably identify the protein complement ...
Romain Drissi +2 more
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Chemical proteomics for subcellular proteome analysis
Current Opinion in Chemical Biology, 2019Protein functions are tightly regulated by their subcellular localization and dynamic alteration. Chemical proteomics offers convenience and efficiency for profiling protein features in a native context. In this review, we summarize the recent progress of subcellular-compartment-focused chemical proteomics which do not rely on organelle fractionation ...
Hao Zhu, Tomonori Tamura, Itaru Hamachi
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