Results 321 to 330 of about 784,733 (395)

Post‐Translational Modifications in Cilia and Ciliopathies

Advanced Science, EarlyView.
This review synthesizes current understanding of post‐translational modifications (PTMs) in ciliary proteins and emphasizes their roles in ciliary formation, homeostasis, and signaling. This review also discusses the implication of PTM dysregulation in ciliopathies and explores therapeutic strategies targeting PTM‐modifying enzymes.
Jie Ran, Jun Zhou
wiley   +1 more source

Nuclear envelope proteomics: Novel integral membrane proteins of the inner nuclear membrane

, 2001
Mathias Dreger, Luiza Bengtsson, Torsten Schöneberg, Henning Otto, Ferdinand Hucho   +4 more
openalex   +1 more source

Application of the Human Proteome in Disease, Diagnosis, and Translation into Precision Medicine: Current Status and Future Prospects. [PDF]

Biomedicines
Xie Y, Chen X, Xu M, Zheng X.
europepmc   +1 more source

Nuclear‐Localized BCKDK Facilitates Homologous Recombination Repair to Support Breast Cancer Progression and Therapy Resistance

Advanced Science, EarlyView.
Under DNA damage, tumor cells rely on efficient DNA repair for survival and therapy resistance. This study has demonstrated that BCKDK localizes to breast cancer cell nuclei, where it binds to and phosphorylates RNF8, thereby blocking ubiquitin‐mediated degradation of RAD51 and enhancing HRR. A selective BCKDK inhibitor synergizes with clinical agents,
Haiying Liu, Jiaqian Feng, Tingting Pan, Pinggen Zhang, Ling Ye, Zetan Jiang, Zilong Zhou, Qiankun Mao, Jian Li, Xinyi Yang, Ping Gao, De Huang, Huafeng Zhang   +12 more
wiley   +1 more source

A mini-review: Proteomic analysis, a post-genomic approach

, 2000
Jean-François Chich
openalex   +1 more source

Directed Proteomics Identifies a Plant-Specific Protein Rapidly Phosphorylated in Response to Bacterial and Fungal Elicitors

, 2001
Scott C. Peck
openalex   +2 more sources

StageTip: a little giant unveiling the potential of mass spectrometry-based proteomics. [PDF]

Anal Sci
Kanao E, Ishihama Y.
europepmc   +1 more source

Collaborative Duality of CircGLIS3(2) RNA and Protein in human Wound Repair

Advanced Science, EarlyView.
CircGLIS3(2), a circRNA transiently upregulated in dermal fibroblasts during acute wound healing, is induced by IL‐1α and TGF‐β. Its RNA activates fibroblasts into matrix‐secreting cells, while its encoded protein enhances proliferation. The RNA stabilizes PCOLCE, and the protein interacts with BTF3, collectively accelerating wound repair. Abstract The
Guanglin Niu, Maria A. Toma, Jennifer Geara, Xiaowei Bian, Yongjian Chen, Lihua Luo, Qizhang Wang, Yunting Xiao, Manika Vij, Minna Piipponen, Zhuang Liu, Sho Oasa, Letian Zhang, Dörte Schlesinger, Ákos Végvári, Dongqing Li, Aoxue Wang, Vladana Vukojević, Simon J Elsässer, Pehr Sommar, Ning Xu Landén   +20 more
wiley   +1 more source

Rapid assay development for low input targeted proteomics using a versatile linear ion trap. [PDF]

Nat Commun
Shannon AE, Teodorescu RN, Song NJ, Heil LR, Jacob CC, Remes PM, Li Z, Rubinstein MP, Searle BC.   +8 more
europepmc   +1 more source

Neophytadiene, a Plant Specialized Metabolite, Mediates the Virus‐Vector‐Plant Tripartite Interactions

Advanced Science, EarlyView.
Tomato chlorosis virus (ToCV) infection induces production of neophytadiene, a volatile resulting from chlorophyll degradation that is highly attractive to whiteflies. OBP2, an odorant‐binding protein from insect vector B. tabaci, exhibits a strong binding affinity for neophytadiene.
Xiao‐bin Shi, Hao Yue, Yan Wei, Evan L. Preisser, Pei Wang, Jiao Du, Ji‐xing Xia, Kai‐long Li, Xin Yang, Jian‐bin Chen, Song‐bai Zhang, Zhan‐hong Zhang, Xu‐guo Zhou, De‐yong Zhang, Yong Liu   +14 more
wiley   +1 more source