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A model for random sampling and estimation of relative protein abundance in shotgun proteomics.
Analytical Chemistry, 2004Proteomic analysis of complex protein mixtures using proteolytic digestion and liquid chromatography in combination with tandem mass spectrometry is a standard approach in biological studies.
Hongbin Liu, R. Sadygov, J. Yates
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The emerging role of mass spectrometry-based proteomics in drug discovery
Nature reviews. Drug discovery, 2022F. Meissner +3 more
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The MaxQuant computational platform for mass spectrometry-based shotgun proteomics
Nature Protocols, 2016Stefka Tyanova +2 more
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2007
Proteomics has been widely applied to several biomedical fields in recent years. The high-throughput capability of proteomics allows simultaneous examination of numerous proteins and offers the possibility of a global analysis of proteins in cells, tissues or biofluids.
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Proteomics has been widely applied to several biomedical fields in recent years. The high-throughput capability of proteomics allows simultaneous examination of numerous proteins and offers the possibility of a global analysis of proteins in cells, tissues or biofluids.
openaire +2 more sources
Single-pot, solid-phase-enhanced sample preparation for proteomics experiments
Nature Protocols, 2018Christopher S. Hughes +5 more
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Spatial proteomics: a powerful discovery tool for cell biology
Nature reviews. Molecular cell biology, 2019E. Lundberg, Georg H. H. Borner
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