Results 71 to 80 of about 218,532 (388)

Lysosome‐Acidifying Nanoparticles Rescue A30P α‐Synuclein Induced Neuronal Death in Cellular and Drosophila Models of Parkinson's Disease

Advanced Healthcare Materials, EarlyView.
Lysosome‐targeted acidic nanoparticles based on a biodegradable poly(ethylene tetrafluorosuccinate‐co‐succinate) copolymer are engineered to restore impaired lysosomal acidification through pH‐responsive intracellular degradation. Localized acid release enhances autophagic proteolysis, reduces α‐synuclein accumulation, and preserves dopaminergic neuron
Chih Hung Lo, Mengda Ren, Gavin Wen Zhao Loi, Eka Norfaishanty Saipuljumri, Jonathan Indajang, Kah Leong Lim, Jialiu Zeng   +6 more
wiley   +1 more source

SKOOTS: Skeleton‐Oriented Object Segmentation for Mitochondria in High‐Resolution Cochlear EM Datasets

Advanced Science, EarlyView.
Skeleton‐oriented object segmentation (SKOOTS) introduces a new strategy for 3D mitochondrial instance segmentation by predicting explicit skeletons rather than relying on boundary cues. This approach enables robust analysis of densely packed organelles in large FIB‐SEM datasets.
Christopher J. Buswinka, Richard T. Osgood, Hidetomi Nitta, Artur A. Indzhykulian   +3 more
wiley   +1 more source

Complicated pyelonephritis caused by Proteus alimentorum in a woman with peritoneal cancer: a case report

BMC Infectious Diseases, 2023
Background Proteus spp. are widespread in the environment and comprise a part of the normal flora of the human gastrointestinal tract. Only six species in this genus, including Proteus mirabilis, Proteus vulgaris, Proteus terrae, Proteus penneri, Proteus
Nobuaki Mori, Jun Hirai, Daisuke Sakanashi, Mina Takayama, Akiko Nakamura, Hirotoshi Ohta, Nobuhiro Asai, Hiroshige Mikamo   +7 more
doaj   +1 more source

Multi‐Enzyme Mimetic Molybdenum Nitride Nanozymes Reshape Subgingival Microenvironment for Synergistic Periodontitis Therapy via ROS Regulation and Microbiome Remodeling

Advanced Science, EarlyView.
ABSTRACT Periodontitis, a chronic inflammatory disease initiated and sustained by plaque microorganisms and host immune response, remains an intractable oral disease and a leading cause of tooth loss worldwide. Traditional mechanical debridement and adjunctive antibiotic or antiseptic therapy often shows limited efficacy due to the complex anatomical ...
Weiyu Zhang, Zhongwei Yang, Yunfan Zhang, Longwei Wang, Xiaoyu Zhang, Jiahui Mao, Yizhi Dai, Yifan Yuan, Mingge Wang, Xin Yang, Xin Yu, Jing Liu, Chunying Chen   +12 more
wiley   +1 more source

Determination of the incidence of Salmonella contamination of eggs being consumed in Shiraz

Majallah-i Dānishgāh-i ̒Ulūm-i Pizishkī-i Bābul, 2000
Objective: This descriptive study was conducted to determine the incidence of salmonella contamination of eggs being consumed in Shiraz. Methods: 500 eggs were selected randomly at different times on a basis of random sampling from four centers of egg ...
AA Jamshidi
doaj  

Etiological cause of Secondary Infection in Acute Conjunctivitis Epidemic at Regional Eye Hospital, Warangal [PDF]

Perspectives In Medical Research, 2017
Background: The aim of this study was to investigate the various etiological causes of secondary infection in acute conjunctivitis epidemic Materials & Methods: Prospective study of 100 patients with acute conjunctivitis presented to Govt Regional ...
K. Vijay Kumar1 , G R Bharath Kumar2 , Anthony Vipin3
doaj  

PENGARUH PENGGUNAAN MEDIA SOFTWARE SIMULASI PROTEUS TERHADAP PRESTASI BELAJAR SISWA PADA MATA DIKLAT ELEKTRONIKA [PDF]

, 2012
Penelitian ini bertujuan untuk mengetahui perbedaan prestasi belajar siswa kelas X1 Kelas A dan Kelas B jurusan Teknik Instalasi Tenaga Listrik SMK 1 Sedayu pada mata diklat Elektronika dengan menerapkan media software simulasi proteus sebagai media ...
Yana Andri, Ariyanto
core  

Evaluation of the efficacy and safety of high dose short duration enrofloxacin treatment regimen for uncomplicated urinary tract infections in dogs. [PDF]

, 2012
BackgroundUncomplicated urinary tract infections (UTI) in dogs usually are treated with antimicrobial drugs for 10-14 days. Shorter duration antimicrobial regimens have been evaluated in human patients.HypothesisA high dose short duration (HDSD ...
Chew, DJ, Daniels, JB, Irom, S, Keil, D, Settje, T, Smith, A, Sykes, JE, Wang, Y, Westropp, JL   +8 more
core   +1 more source

Circular RNA circNrip1 Interacts with SYNCRIP to Promote Neuropathic Pain by Stabilizing Tlr2 mRNA in Primary Sensory Neurons

Advanced Science, EarlyView.
Model of circNrip1 (cNrip1) upregulation driving neuropathic pain mechanisms. After peripheral nerve injury, increased FUS triggers the formation and upregulation of cNrip1 in injured DRG neurons. Upregulated cNrip1 recruits SYNCRIP to the 3′‐UTR of Tlr2 mRNA by binding to both, thereby promoting SYNCRIP‐triggered Tlr2 mRNA stability and increasing ...
Xiaozhou Feng, Jifang Xiao, Congcong Huang, Bao‐Chun Jiang, Bing Wang, Xu Li, Shibin Du, Tolga Berkman, Chun‐Hsien Wen, Weihua Cai, Dilip Sharma, Kun Wang, Longfei Ma, Huijuan Hu, Yuan‐Xiang Tao   +14 more
wiley   +1 more source

Prototype of Wireless Torque Sensor on Truck Rotary Shaft

Механика машин, механизмов и материалов, 2018
The paper presents principle scheme of wireless torque sensor on rotary shafts, for example truck cardan shaft, to measure dynamic torque of transmission in range of 0…10 kNm, also describes designing and manufacturing method.
Van Nghia Le, Phuong Le Ngo, Trong Hoan Nguyen   +2 more
doaj