Results 91 to 100 of about 218,532 (388)

Biofilm is a major virulence determinant in bacterial colonization of chronic skin ulcers independently from the multidrug resistant phenotype [PDF]

open access: yes, 2017
Bacterial biofilm is a major factor in delayed wound healing and high levels of biofilm production have been repeatedly described in multidrug resistant organisms (MDROs).
Bordignon, Valentina   +15 more
core   +2 more sources

Enzymatic Basis for the Oxidative Branch of Aromatic Amino Acid Fermentation Leading to p‐cresol Formation

open access: yesAdvanced Science, EarlyView.
In anaerobic bacteria, tyrosine serves as an electron donor in the oxidative Stickland fermentation branch, generating p‐hydroxyphenylacetate, ATP and reduced ferredoxin for decarboxylation into p‐cresol. ABSTRACT The phenolic metabolite p‐cresol is a byproduct of tyrosine fermentation by certain strictly anaerobic bacteria, including the human gut ...
Li Jiang   +15 more
wiley   +1 more source

Comparison of Receptor‐Mediated Endocytosis and Its Application to Enhance DNA Transfection by TFAMoplex

open access: yesAdvanced NanoBiomed Research, EarlyView.
We developed an assay to distinguish cellular binding from internalization. Compatible with microscopy and high‐throughput screening, the method identifies ligand‐mediated uptake. Applying top candidates to a protein‐based DNA carrier enhanced transfection efficiency, providing a rational strategy to improve non‐viral gene delivery systems.
David Scherer   +5 more
wiley   +1 more source

Spondyloarthritis Preceding and Following Inflammatory Bowel Disease Diagnosis and Risk Factors: A Temporal Trends Analysis in a Population‐Based Cohort

open access: yesArthritis &Rheumatology, EarlyView.
Objective Spondyloarthritides (SpA) and inflammatory bowel disease (IBD) are immune‐mediated diseases with overlap in clinical and immunologic features. However, temporal correlation of SpA and IBD in individual patients and risk factors are not well characterized.
Manasi Agrawal   +6 more
wiley   +1 more source

Hearts and Minds: The Untold Story of How Philanthropy and the Civil Marriage Collaborative Helped America Embrace Marriage Equality [PDF]

open access: yes, 2014
In 2004, a group of foundations came together to create a funder collaborative in support of Freedom to Marry's state-by-state strategy to win marriage equality.

core  

Orpheus and 'second nature' in Francis Bacon [PDF]

open access: yes, 2018
open1noWhile Francis Bacon’s interpretations of mythological figures such as those of Prometheus, Proteus and Vulcan have received quite a bit of attention by scholars, the myth of Orpheus shows a wealth of meanings almost entirely still to be explored ...

core   +1 more source

Proteus (Proteus)

open access: yesGoethe-Lexicon of Philosophical Concepts
Beginning with his botanical epiphany in Sicily in 1787, Goethe turned to the ancient Greek sea god Proteus as a key figure for imagining natural metamorphosis. “Proteus” is perhaps a surprising term for a lexicon of philosophical concepts. Its connection to symbol, myth, and what Hegel would call representational thinking (Vorstellungsdenken ...
openaire   +1 more source

Environmental DNA in subterranean biology: range extension and taxonomic implications for Proteus

open access: yesScientific Reports, 2017
Europe’s obligate cave-dwelling amphibian Proteus anguinus inhabits subterranean waters of the north-western Balkan Peninsula. Because only fragments of its habitat are accessible to humans, this endangered salamander’s exact distribution has been ...
S. Goricki   +9 more
semanticscholar   +1 more source

Digital diagnostics, biomarkers and therapeutics in an evolving healthcare system: From promise to practice

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
Abstract Health care is shifting towards a digital‐guided system, integrating digital diagnostics, biomarkers and therapeutics in many care pathways. However, despite rapid technological advancement and preliminary adoption accelerated by the COVID‐19 pandemic, a significant implementation gap persists. This narrative review explores the causes of this
Mees H. P. Stoop   +3 more
wiley   +1 more source

The water clock of Proteus mirabilis paces colony periodic and synchronous swarming [PDF]

open access: yes, 2010
For decades, the origin of the concentric ring pattern of bacterial swarming colonies has puzzled microbiologists. Thanks to _in situ_ and real time infrared microspectroscopy and the brilliance of the infrared beam at SOLEIL synchrotron, we demonstrate ...
Elodie Lahaye   +2 more
core   +1 more source

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