Results 51 to 60 of about 1,158,693 (154)

A Case of Proteus Syndrome with Hemangioma Presentation

open access: yesJournal of Clinical and Basic Research, 2018
Background: Proteus syndrome is a rare genetic disorder characterized by overgrowth of bones, skin, and other tissues, with vascular malformations, epidermal moles, and subcutaneous masses.
Jabbar Parhiz   +3 more
doaj   +2 more sources

The potential for biased signalling in the P2Y receptor family of GPCRs

open access: yesBritish Journal of Pharmacology, EarlyView.
The purinergic receptor family is primarily activated by nucleotides, and contains members of both the G protein coupled‐receptor (GPCR) superfamily (P1 and P2Y) and ligand‐gated ion channels (P2X). The P2Y receptors are widely expressed in the human body, and given the ubiquitous nature of nucleotides, purinergic signalling is involved with a plethora
Claudia M. Sisk   +2 more
wiley   +1 more source

Approach in an adolescent Proteus male patient with megafoot

open access: yesThe Turkish Journal of Pediatrics, 2008
Proteus syndrome is a rare overgrowth syndrome characterized by hemihypertrophy, lower limb asymmetry, hyperpigmentations, lipomas, and vascular malformation.
Orhan Derman, Sevim Balci, Ozlem Engiz
doaj  

Unilateral hypertrophic skin lesions, hemimegalencephaly, and meningioma: The many faces of Proteus syndrome

open access: yesIndian Dermatology Online Journal, 2015
Proteus syndrome is a rare condition with a wide spectrum of abnormalities. It is characterized by hamartomatous malformations involving multiple organs.
Niharika R Lal   +2 more
doaj   +1 more source

sGC stimulator BAY 41‐8543 improves survival and ventricular function in a rat model of doxorubicin‐induced cardiomyopathy with nephrotic syndrome

open access: yesBritish Journal of Pharmacology, EarlyView.
Abstract Background and Purpose Anthracyclines such as doxorubicin (DOXO) remain a cornerstone of cancer therapy but are associated with a high risk of cardiotoxicity and subsequent heart failure (HF). Impairment of NO/soluble guanylyl cyclase (sGC)/cGMP pathway has been reported in anthracycline‐induced cardiomyopathy.
Olga Gawrys   +14 more
wiley   +1 more source

Permission to Rise: Self‐Permission and Career Resilience for Women

open access: yesGender, Work &Organization, EarlyView.
ABSTRACT Women remain underrepresented in leadership and are more likely than men to reduce their workforce participation or step back from their careers, particularly when navigating caregiving responsibilities. Although these aggregate gender differences motivate the present study, our goal is not to explain differences between women and men directly.
Kelly Watson, Jodi Detjen
wiley   +1 more source

Hypercapnia Induces Mitochondrial Adaptations and Alters Glutamine Metabolism to Drive a Distinct Metabolic Phenotype in Monocytes

open access: yesImmunology &Cell Biology, EarlyView.
Elevated CO2 (hypercapnia) is a feature of serious lung diseases, for example COPD and contributes to poor patient prognosis through modulation of immune cell function. Here we employ state‐of‐the art metabolomic and isotope tracing approaches to reveal CO2‐dependent mitochondrial alterations linked to suppressed ATP, proline and glutamate levels in ...
Ben Reddan   +5 more
wiley   +1 more source

Proteus Syndrome: Report of Intra-Abdominal Lipomatosis

open access: yesEuropean Journal of Pediatric Surgery Reports, 2013
Proteus syndrome (PS) is an extremely rare sporadic disorder that manifests as an asymmetric, disproportionate overgrowth of any connective tissues, such as bone, fat, or epidermal nevi, in a mosaic or patchy pattern.
Basak Erginel   +7 more
doaj   +1 more source

A case report of Proteus syndrome (PS)

open access: yesBMC Medical Genetics, 2020
Background Proteus syndrome (PS) is an extremely rare disease characterized by excessive chimeric growth of cells, and progressive and irregular asymmetrical hyperplasia.
Xiaoyun Zeng   +4 more
doaj   +1 more source

Pink Polypoid Papulo‐Vesicles on Labia Majora

open access: yes
JEADV Clinical Practice, EarlyView.
Maria Chiara Mercuri   +3 more
wiley   +1 more source

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