Results 181 to 190 of about 147,027 (351)

Effect of General Anesthesia on Liver and Spleen Stiffness for Predicting High‐Risk Varices in Biliary Atresia

open access: yesHepatology Research, EarlyView.
In children with biliary atresia (BA), breath‐holding during liver and spleen stiffness (LS and SS) measurement is often difficult, raising concerns about measurement reliability in the awake state. We investigated whether performing LS and SS measurements under general anesthesia—when brief ventilation pauses are possible—could improve diagnostic ...
Shinya Yokoyama   +11 more
wiley   +1 more source

Efficacy and Safety of Hypofractionated Radiation Therapy Combined With Immunotherapy for Hepatocellular Carcinoma With Vp4 Portal Vein Tumor Thrombosis

open access: yesHepatology Research, EarlyView.
ABSTRACT Background Hepatocellular carcinoma (HCC) with Vp4 portal vein tumor thrombosis (PVTT) has an extremely poor prognosis, and evidence for effective systemic therapy is limited. Preclinical studies suggest that hypofractionated radiation therapy (HFRT) may enhance immune checkpoint inhibitor (ICI) efficacy through immunogenic cell death and ...
Masahiko Tameda   +11 more
wiley   +1 more source

Transforming Coagulation Testing: The Role of Biosensors in Prothrombin Time (PT) Measurement. [PDF]

open access: yesACS Omega
Weerarathna IN   +5 more
europepmc   +1 more source

Clinical Outcomes of Reduced‐Dose Cabozantinib as Third‐ or Later‐Line Therapy After Immune Checkpoint Inhibitors in Advanced Hepatocellular Carcinoma: A Real‐World Study

open access: yesHepatology Research, EarlyView.
In this real‐world post‐ICI setting, cabozantinib demonstrated meaningful clinical activity even at reduced doses, with disease control achieved in nearly half of patients. Importantly, preserved liver function (Child–Pugh class A) was the only determinant of both disease control and overall survival.
Teiji Kuzuya   +13 more
wiley   +1 more source

Feasibility to infer accurate fibrinogen concentrations from thrombin generation, prothrombin time, or Reptilase time waveforms. [PDF]

open access: yesRes Pract Thromb Haemost
Arisz RA   +7 more
europepmc   +1 more source

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