Results 191 to 200 of about 17,468,048 (391)

Guidelines from the expert advisory committee on the Safety of Blood, Tissues and Organs (SaBTO) on patient consent and shared decision‐making for blood transfusion

open access: yesBritish Journal of Haematology, EarlyView.
The key points to be discussed with a patient when obtaining consent to transfusion are the reason for the transfusion, the benefits and risks of transfusion, the possible alternatives to transfusion, the process for transfusion, any specific transfusion requirements that the patient may have, the consequences of refusing transfusion and the ability to
Michael F. Murphy   +16 more
wiley   +1 more source

RNA Analysis Uncovers Pathogenic PARN Variant in Dyskeratosis Congenita

open access: yesClinical Genetics, EarlyView.
Using WGS and RNA analysis, we identified a branch point‐disrupting variant in the PARN gene and elucidated its pathogenic molecular mechanism in a child with atypical dyskeratosis congenita presentation. ABSTRACT Dyskeratosis congenita (DC) is a rare genetic disorder caused by impaired telomere maintenance, leading to diverse clinical manifestations ...
Daria Akimova   +3 more
wiley   +1 more source

Neonates born at term with periventricular haemorrhagic infarction: Risk factors and clinical presentation

open access: yesDevelopmental Medicine &Child Neurology, EarlyView.
This case series describes infants born near term with periventricular hemorrhagic infarction (PVHI), highlighting seizures as a common early symptom. Neonatal complications during delivery and pro‐thrombotic genetic mutations were slightly more common. MRI‐classified involvement was predominantly in the caudate vein territory.
Aleksandra Zaykova   +6 more
wiley   +1 more source

Acute hepatitis and haemolysis associated with doxycycline and rifampin administration in two weanling foals

open access: yesEquine Veterinary Education, EarlyView.
Summary Two foals were being treated with a combination of oral doxycycline and rifampin for presumed Rhodococcus equi infections. After 3–4 weeks of antimicrobial administration, both foals presented with icterus and nonspecific clinical signs, including lethargy and inappetence.
A. Murdock   +7 more
wiley   +1 more source

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