Results 211 to 220 of about 17,533,570 (258)
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Thromboplastin Time (Prothrombin Time)

1965
Publisher Summary This chapter elaborates thromboplastin time that is, prothrombin time. Blood plasma contains 300–400 mg% fibrinogen, and during coagulation of blood this is converted to insoluble fibrin by thrombin. The highly active enzyme thrombin is formed from an inactive precursor, prothrombin.
openaire   +2 more sources

Prothrombin-Time Methods

JAMA: The Journal of the American Medical Association, 1965
To the Editor:— Oral anticoagulation remains a complicated subject involving many facets, but one variable could be made a constant if the one-stage prothrombin time were carried out by the standard technique outlined over 25 years ago, when I explicitly described the preparation of thromboplastin.
Armand J. Quick, Herbert S. Sise
openaire   +2 more sources

Simplified Prothrombin Time Standardization

Pathophysiology of Haemostasis and Thrombosis, 1994
An analysis of prothrombin time (PT) standardization methods is presented. The present recommended ratio method demonstrated complex calibration and wide therapeutic ranges. Standardization by coagulation activities resulted in different therapeutic ranges due to the different sensitivity of assays for the protein induced by vitamin K absence (Pivka ...
Ingebrigt Talstad, Knut Korsbrekke
openaire   +3 more sources

The prothrombin time test [PDF]

open access: possible, 1992
The prothrombin time (PT) is the screening test for the extrinsic (tissue) clotting system. The PT was originally introduced by Quick1 as a measure of a coagulation defect in the newborn and jaundiced patients, and subsequently adapted for its present principal uses in the screening of extrinsic clotting and in monitoring of oral anticoagulant dosage ...
openaire   +1 more source

Investigation of prothrombin time in human whole-blood samples with a quartz crystal biosensor.

Analytical Chemistry, 2010
Monitoring of blood coagulation and fibrinolysis is an important issue in treatment of patients with cardiovascular problems and in surgery when blood gets into contact with artificial surfaces.
Lothar Müller   +6 more
semanticscholar   +1 more source

The action of Dicumarol in the human being on plasma prothrombin time and total prothrombin time

American Heart Journal, 1952
Abstract In man, Dicumarol causes an increase in the plasma and in the total prothrombin times. The explanation is offered that Dicumarol reduces both the free and total prothrombin and that a rough ratio between the two forms is maintained. The practical significance of this observation is discussed.
Clara V. Hussey   +5 more
openaire   +3 more sources

Prothrombin time (PT) [PDF]

open access: possible, 1999
The prothrombin time (PT) is the screening test for the extrinsic (tissue) clotting system. The PT was originally introduced by Quick1 as a measure of a coagulation defect in the newborn and in jaundiced patients, and subsequently adapted for its present principal uses in the screening of extrinsic clotting and in monitoring of oral anticoagulant ...
openaire   +1 more source

Comparison of a Chromogenic Prothrombin Time with Clotting Prothrombin Time in the Assessment of Clinical Coagulation Deficiencies

American Journal of Clinical Pathology, 1985
A chromogenic prothrombin time (CPT) has been compared with the standard prothrombin time (PT) or activated partial thromboplastin time (aPTT) in evaluating the hemostatic abnormality in patients with specific clotting factor deficiencies or liver disease and in patients receiving anticoagulant or fibrinolytic therapy.
Jane E. Malone   +2 more
openaire   +3 more sources

THE PROTHROMBIN TIME IN DICOUMAROL THERAPY

Annals of Internal Medicine, 1949
Excerpt The identification of dicoumarol as the cause of sweet clover disease was made by Link in 1939.
openaire   +3 more sources

Anticoagulants and Prothrombin Time

Medical Journal of Australia, 1978
S. Gordon, B. G. Firkin
openaire   +4 more sources

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