Results 211 to 220 of about 14,853 (233)
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Effects of Angiotensin 1-7 Binding on the Dynamics of Human MAS Proto-Oncogene, GPCR: A Molecular Dynamics Study

Journal of Computational Biophysics and Chemistry, 2023
The understanding of the connections between Angiotensin peptides with the receptors in the Renin-angiotensin system (RAS) is not clear yet. The ACE2/Ang (1-7)/MAS axis, commonly referred to as the protective arm of the RAS, plays a crucial role in maintaining homeostasis within the cardiovascular system.
Ekrem Yasar   +4 more
openaire   +1 more source

Selective expression of c-mas proto-oncogene in rat cerebral endothelial cells

NeuroReport, 1996
Northern blot analysis of cultured endothelial cells derived from rat cerebral resistance vessels demonstrated the presence of c-mas mRNA. This is the first description of mas expression in non-neuronal cells. c-mas message was not detectable in cultured endothelial cells derived from other vascular beds, including rat aorta and mesenteric resistance ...
M, Kumar   +3 more
openaire   +2 more sources

The mas proto-oncogene is developmentally regulated in the rat central nervous system

Developmental Brain Research, 1992
The mas proto-oncogene encodes a protein with a predicted structure similar to members of the family of seven transmembrane domain spanning receptors. These receptors are thought to transduce extracellular signals to G-proteins. Angiotensin II and III have been reported to be the functional ligands for the mas oncogene-encoded receptor (Jackson et al.,
K A, Martin, S G, Grant, S, Hockfield
openaire   +2 more sources

Expression of the mas proto-oncogene in the rat hippocampal formation is regulated by neuronal activity

Molecular Brain Research, 1993
The mas proto-oncogene encodes a seven membrane-spanning G-protein-coupled receptor which is activated by angiotensins. In the postnatal and adult rat, mas mRNA is specifically expressed at high levels in hippocampal neurons. We report here using in situ hybridization and RNase protection that brief seizure episodes lead to a significant and transient ...
K A, Martin, S, Hockfield
openaire   +2 more sources

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