Results 191 to 200 of about 440,834 (358)

Phosphorylated Proto-Oncogene Tyrosine-Protein Kinase Src [PDF]

, 2020
openaire   +1 more source

NFS1 Regulates IDH2 to Attenuate Abdominal Aortic Aneurysms via Interacting With SP2

Advanced Science, EarlyView.
The loss of NFS1 leads to its reduced binding with the transcription factor SP2, resulting in decreased expression of the downstream gene Idh2. This causes a shift in energy supply toward glycolysis in VSMCs, ultimately contributing to the occurrence and progression of AAA.
Luzheng Zhang, Yu Zhang, Dezhong Wen, Suxiang Guo, Xiaohui Qi, Heng Wang, Yujin Sun, Guangdong Yang, Yuehong Wang, Song Xue   +9 more
wiley   +1 more source

Perfluorooctanoic Acid Exposure Causes Macrophage Ammonia Retention and Induces Spontaneous Miscarriages

Advanced Science, EarlyView.
PFOA exposure induces pregnancy loss by promoting glutaminolysis, which further causes ammonia accumulation in macrophages. Cellular ammonia retention results in damage to mitochondria and lysosomes, which leads to cell death eventually. Impaired lysosomes also decrease the secretion of the Cathepsin B (CTSB), and attenuate macrophage infiltration and ...
Yongbo Zhao, Yijun Zhang, Hanyu Rao, Jiani Sun, Zhiyi Pan, Liping Jin, Yan Zhao   +6 more
wiley   +1 more source

Proto-oncogene Activity of Melanoma Antigen-A11 (MAGE-A11) Regulates Retinoblastoma-related p107 and E2F1 Proteins

, 2013
Shifeng Su, John T. Minges, Gail Grossman, Amanda J. Blackwelder, James L. Mohler, Elizabeth M. Wilson   +5 more
openalex   +1 more source

The mRNA-binding protein HuR promotes hypoxia-induced chemoresistance through posttranscriptional regulation of the proto-oncogene PIM1 in pancreatic cancer cells [PDF]

, 2015
Fernando F. Blanco, Masaya Jimbo, J. D. Wulfkuhle, Isela Gallagher, Jing Deng, Liz Enyenihi, Nicole Meisner‐Kober, Eric Londin, Isidore Rigoutsos, Janet A. Sawicki, Makarand V. Risbud, Agnieszka K. Witkiewicz, Peter A. McCue, Wei Jiang, Hallgeir Rui, Charles J. Yeo, Emanuel F. Petricoin, Jordan M. Winter, Jonathan R. Brody   +18 more
openalex   +1 more source

RAF Proto-Oncogene Serine/Threonine-Protein Kinase [PDF]

, 2020
openaire   +1 more source

Molecular genetics of development studied in the transgenic mouse. [PDF]

, 1989
Gruss, P., Westphal, H.
core   +2 more sources

METTL1‐Mediated M7G tRNA Modification Promotes Residual Liver Regeneration After Hepatectomy via Translational Control

Advanced Science, EarlyView.
METTL1 and its mediated m7G tRNA modification are significantly up‐regulated after partial hepatectomy (PHx). Overexpression of METTL1 improves the efficiency of liver regeneration after PHx, increases the proliferation of hepatocytes, and accelerates the recovery of liver function.
Manling Huang, Shuirong Lin, Yutong Zhao, Jiale Chen, Linyuan Huang, Yuyao Liu, Zixin Huang, Dongxin An, Yifan Zhang, Zimin Song, Xi Yu, Yunpeng Hua, Jing Wang, Weiwei Wang, Yu Guo, Ming Kuang, Fang Wang, Shuibin Lin, Shunli Shen   +18 more
wiley   +1 more source

[Retracted] 8‑bromo‑7‑methoxychrysin induces apoptosis by regulating Akt/FOXO3a pathway in cisplatin‑sensitive and resistant ovarian cancer cells [PDF]

Mol Med Rep
Ding Q, Chen Y, Zhang Q, Guo Y, Huang Z, Dai L, Cao S.   +6 more
europepmc   +1 more source

Identification of protein products encoded by the proto-oncogene int-1.

, 1987
Anthony M.C. Brown, J Papkoff, Y K Fung, Gregory M. Shackleford, Harold Varmus   +4 more
openalex   +2 more sources