Results 261 to 270 of about 440,834 (358)

Helicobacter pylori Activates Mitogen-activated Protein Kinase Cascades and Induces Expression of the Proto-oncogenes c-fos and c-jun [PDF]

, 2000
Tobias Meyer‐ter‐Vehn, Antonello Covacci, Manfred Kist, Heike L. Pahl   +3 more
openalex   +1 more source

OTUD6A in Airway Epithelial Cells Exacerbates Allergic Asthma by Promoting Airway Inflammation and Airway Remodeling Through Deubiquitination of hResistin/mRELMα

Advanced Science, EarlyView.
This study elucidates a novel mechanistic role of the deubiquitinase OTUD6A in asthma pathogenesis, uncovering its regulatory function in airway inflammation and airway remodeling through the stabilization of hResistin/mRELMα. This study offers a novel regulatory axis (OTUD6A‐hResistin/mRELMα) in asthma pathogenesis and OTUD6A inhibition as a potential
Weiting Pan, Xinru Xi, Wei Dai, Tingfang Xiao, Yeqing Chen, Xuanyu Chen, Xiangting Ge, Chengguang Zhao, Hui Zhang, Yali Zhang, Weixi Zhang   +10 more
wiley   +1 more source

SLC39A5 promotes the malignant progression of gastric cancer by activating BATF phosphorylation. [PDF]

J Biol Chem
Wang X, Li T, Xia M, Sun L, Wang X.
europepmc   +1 more source

Biomimetic Nanomedicine for Senescence‐Modulated Immune Activation Enhances Immunotherapy Efficacy in Hepatocellular Carcinoma

Advanced Science, EarlyView.
A multifunctional mPDZM nanoplatform is developed in this study. mPDZM integrates chemotherapy‐induced senescence, selective senolysis, and STING‐mediated immune activation. mPDZM effectively clears senescent tumor cells, remodels the tumor immune microenvironment, and enhances antitumor T‐cell responses.
Shiji Fang, Liyun Zheng, Bin Lin, Jiale Chen, Dehai Hou, Yiming Ding, Mengzhu Han, Pan Qin, Mengyuan Wang, Xiaoju Guo, Yeyu Zhang, Gaofeng Shu, Fazong Wu, Jianfei Tu, Minjiang Chen, Zhongwei Zhao, Zhuang Liu, Jiansong Ji   +17 more
wiley   +1 more source

Network pharmacology combined with ultra-high-performance liquid chromatography-quadrupole time-of-flight mass spectrometry method to explore the mechanism of Shizhi Fang in treating uric acid nephropathy mice. [PDF]

J Tradit Chin Med
Feng Y, Xuming Z, Zhiyuan WU, Jiandong G.   +3 more
europepmc   +1 more source

Immunohistochemistry in Anaplastic Lymphoma Kinase and Proto-Oncogene Tyrosine-Protein Kinase ROS [PDF]

Archives of Pathology & Laboratory Medicine, 2018
openaire   +2 more sources

Oncolytic Probiotics with Molecular Pili for Solid Tumor Therapy

Advanced Science, EarlyView.
This study identifies Lactobacillus rhamnosus as an intrinsic oncolytic agent that triggers tumor metabolic collapse via calcium‐dependent ROS bursts. By chemically anchoring collagen‐targeting “molecular pili” to the bacterial surface, the engineered non‐transgenic probiotic (LR@MP) achieves targeted colonization and potent solid tumor suppression ...
Haodong Ge, Chengsheng Ding, Xiao Yang, Si Gao, Changjie Yang, Yuchen Hou, Hongye Wang, Linke Bian, Hao Zhong, Yifan Qu, Luyang Zhang, Junjun Ma, Zhengwei Cai, Wenguo Cui, Minhua Zheng   +14 more
wiley   +1 more source

Reply to correspondence 2 on “MET promotes hepatocellular carcinoma development through the promotion of TRIB3-mediated FOXO1 degradation” [PDF]

Clinical and Molecular Hepatology
Ji Eun Han, Soon Sun Kim, Jae Youn Cheong, Jung Woo Eun   +3 more
doaj   +1 more source

Integrated analysis of ARHGAP6 potential function and prognostic value in acute myeloid leukemia. [PDF]

PLoS One
Yang D, Li Y, Ma P, Xiao F.
europepmc   +1 more source

A Short-Lived Nuclear Phosphoprotein Encoded by the Human ets-2 Proto-Oncogene Is Stabilized by Activation of Protein Kinase C

, 1988
Shigeyoshi Fujiwara, Robert J. Fisher, Narayan Bhat, Susana Moreno Dı́az de la Espina, Takis S. Papas   +4 more
openalex   +2 more sources