Results 21 to 30 of about 440,834 (358)

Association of thevavproto-oncogene product with poly(rC)-specific RNA-binding proteins [PDF]

open access: bronzeMolecular and Cellular Biology, 1995
Xosé R. Bustelo   +4 more
openalex   +2 more sources

Correlation of long interspersed element-1 open reading frame 1 and c-Met proto-oncogene protein expression in primary and recurrent colorectal cancers [PDF]

open access: yesKosin Medical Journal, 2022
Background Colorectal cancer is one of the most common cancers worldwide. Colorectal cancer that has recurred and metastasized to other organs also has a very poor prognosis.
Kyung-Yoon Jeon   +6 more
doaj   +1 more source

Mutation of Vav1 adaptor region reveals a new oncogenic activation [PDF]

open access: yes, 2014
International audienceVav family members function as remarkable scaffold proteins that exhibit both GDP/GTP exchange activity for Rho/Rac GTPases and numerous protein-protein interactions via three adaptor Src-homology domains.
Cormier, Françoise   +7 more
core   +12 more sources

Interplay of the Proto-oncogene Proteins CrkL and CrkII in Insulin-like Growth Factor-I Receptor-mediated Signal Transduction*

open access: yesJournal of Biological Chemistry, 1998
The closely related proto-oncogene proteins CrkII and CrkL consist of one SH2 and two SH3 domains and share 60% overall homology with the highest identity within their functional domains. In this study we show that CrkL and CrkII may play overlapping but
A. Koval, M. Karas, Y. Zick, D. Leroith
semanticscholar   +1 more source

LncRNA Snhg1, a non-degradable sponge for miR-338, promotes expression of proto-oncogene CST3 in primary esophageal cancer cells

open access: yesOncoTarget, 2017
Competing endogenous RNA (ceRNA) is a newly proposed mechanism that describes a crosstalk among lncRNAs, mRNAs and their shared miRNAs. In this study, the role of miR-338-3p (miR-338) in the progression of esophageal cancer and its involve in the ceRNA ...
Yan Yan   +5 more
semanticscholar   +1 more source

Subcellular Localization of the Human Proto-oncogene Protein DEK [PDF]

open access: yesJournal of Biological Chemistry, 2001
Recent data revealed that DEK associates with splicing complexes through interactions mediated by serine/arginine-repeat proteins. However, the DEK protein has also been shown to change the topology of DNA in chromatin in vitro. This could indicate that the DEK protein resides on cellular chromatin.
F, Kappes   +4 more
openaire   +2 more sources

Wnt/beta-catenin/Tcf signaling: A critical pathway in gastrointestinal tumorigenesis [PDF]

open access: yes, 2002
Cancers of the gastrointestinal tract, including the liver, bile ducts, and pancreas, constitute the largest group of malignant tumors. Colorectal cancer is one of the most common neoplastic diseases in Western countries and one of the leading causes of ...
Bommer, G., Göke, B., Kolligs, F. T.
core   +2 more sources

Primary colonic liposarcomatosis: report of a case with review of literature

open access: yesAutopsy and Case Reports, 2019
LiposarcomaThe colon is a rare site of occurrence of liposarcoma, as either the primary site or by secondary involvement from a retroperitoneal liposarcoma. Liposarcomatosis denotes simultaneous occurrence of multiple liposarcomas.
Mahesh Sultania   +4 more
doaj   +1 more source

The association of BRAF V600E gene mutation with proliferative activity and histopathological characteristics of congenital melanocytic nevi in children

open access: yesAnais Brasileiros de Dermatologia, 2023
Background: A lot of congenital melanocytic nevi (CMN) carry the somatic mutation in the oncogene BRAF V600E. But the detailed histopathologic characteristics and the proliferative activity of CMN with BRAF V600E gene mutation have not been ...
Jianyou Chen   +3 more
doaj   +1 more source

Glutathione Metabolism in Renal Cell Carcinoma Progression and Implications for Therapies [PDF]

open access: yes, 2019
A significantly increased level of the reactive oxygen species (ROS) scavenger glutathione (GSH) has been identified as a hallmark of renal cell carcinoma (RCC). The proposed mechanism for increased GSH levels is to counteract damaging ROS to sustain the
Meierhofer, David, Xiao, Yi
core   +2 more sources

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