Results 101 to 110 of about 49,863 (128)

Langerhans cell histiocytosis manifesting at birth: a neonatal case with BRAF V600E mutation. [PDF]

Diagn Pathol
Tang W, Wang P.
europepmc   +1 more source

Broad-Spectrum RAS Inhibition in Pancreatic Ductal Adenocarcinoma: Mechanistic Advances and Therapeutic Promise. [PDF]

Pharmaceuticals (Basel)
Alanazi FE, Alatawi Y, Alattar A, Alshaman R, Kotb AA, Hetta HF.   +5 more
europepmc   +1 more source

<i>RGS4</i> in gastric cancer: A multifaceted regulator of focal-adhesion-kinase -phosphatidyl-inositol-3-kinase - protein-kinase-B signaling and epithelial-mesenchymal transition beyond tumor progression. [PDF]

World J Gastroenterol
Yang Y, Chen WM.
europepmc   +1 more source

Pathway-Specific Therapeutic Modulation of Melanoma: Small-Molecule Inhibition of BRAF-MEK and KIT Signaling in Contemporary Precision Oncology with a Special Focus on Vemurafenib, Trametinib, and Imatinib. [PDF]

J Clin Med
Kawczak P, Bączek T.
europepmc   +1 more source

The BRAF-specific region suppresses cysteine-rich domain-lipid interaction independently of canonical autoinhibition by the 14-3-3 dimer. [PDF]

Protein Sci
Revazishvili V, Morales A, Baxter B, Grim J, Chakhrakia A, Jimenez Salinas A, Tevdorashvili K, Riestra AM, Lee YK.   +8 more
europepmc   +1 more source

ets-2 is a target for an akt (Protein kinase B)/jun N-terminal kinase signaling pathway in macrophages of motheaten-viable mutant mice [PDF]

, 2000
Forsthoefel, D, Hartman, M, Hofmeister, J K, Hume, D A, Ostrowski, M C, Schaffner, A E, Smith, J L, Wei, G   +7 more
core  

An overview of mechanisms, biomarkers, and treatment strategies for acquired anti-EGFR resistance in RAS wild-type colorectal cancer. [PDF]

Front Pharmacol
Ding C, Yao R, Wang Y, Liu H, Li C, Xie H.   +5 more
europepmc   +1 more source

BRAF inhibitor or BRAF/MEK inhibitor treatment for patients with metastatic BRAF V600E mutated differentiated thyroid cancer. [PDF]

Arch Endocrinol Metab
Finkel I, Korzets Y, Moore A, Coreanu T, Popovtzer A, Shoffel-Havakuk H, Bachar G, Mansour J, Weiss C, Robenshtok E.   +9 more
europepmc   +1 more source

大腸粘膜上皮細胞の恒常性と炎症における、Spred2の新たな役割 [PDF]

, 2017
Takahashi, Sakuma
core  

An in vitro BRAF activation assay elucidates molecular mechanisms driving disassembly of the autoinhibited BRAF state. [PDF]

Proc Natl Acad Sci U S A
Ritt DA, Durrant DE, Drew MR, Sandin SI, Martinez Fiesco JA, Zhang X, Aydin F, Carpenter TS, Scheidemantle GM, D'Ippolito RA, Sohn AL, DeHart CJ, Shrestha R, Snead K, Hull J, Tempkin JOB, Yang Y, Lightstone FC, Streitz FH, Zhang P, Turbyville TJ, Stephen AG, Esposito D, Ingólfsson HI, Nissley DV, Morrison DK.   +25 more
europepmc   +1 more source