Results 71 to 80 of about 49,863 (128)

Biochemical and Physiological Effects of Galanin in Health and Disease

The FASEB Journal, Volume 40, Issue 2, 31 January 2026.
Galanin is a biologically active neuropeptide hormone that mediates its effects through three galanin receptors. Galanin signaling induces changes in glucose homeostasis amongst others and plays a dynamic role in the physiological health of many organ systems.
Patrick Mireles, Yubo Wang, Kathryn Rhodes, Sharon DeMorrow   +3 more
wiley   +1 more source

Frontiers in Pigment Cell and Melanoma Research

, 2018
We identify emerging frontiers in clinical and basic research of melanocyte biology and its associated biomedical disciplines. We describe challenges and opportunities in clinical and basic research of normal and diseased melanocytes that impact current ...
Birlea, Stanca, Bosenberg, Marcus W., Box, Neil F., Brash, Douglas, Cassidy, Pamela B., Chen, Suzie, D'Orazio, John August, Filipp, Fabian V., Fujita, Mayumi, Goh, Boon-Kee, Herlyn, Meenhard, Indra, Arup K., Larue, Lionel, Leachman, Sancy A., Liu-Smith, Feng, Manga, Prashiela, Montoliu, Lluis, Norris, David A., Poole, Caroline Le, Shellman, Yiqun, Smalley, Keiran S. M., Spritz, Richard A., Sturm, Richard A., Swetter, Susan M., Terzian, Tamara, Wakamatsu, Kazumasa, Weber, Jeffrey S.   +26 more
core   +1 more source

Defining the clinical role of the mammalian target of rapamycin (mTOR) in lung cancer

, 2010
Lung cancer is the biggest cancer killer. Most patients present with advanced disease. These diseases are not amenable to surgery which currently provides the best chance of cure.
Dhillon, Perminder Tony Singh, Dhillon, Perminder Tony Singh   +1 more
core   +1 more source

Pattern of expression of the jun family of transcription factors during the early development of the inner ear: implications in apoptosis [PDF]

, 1999
8 pages, 6 figures, 1 table.Jun transcription factors have been implicated in the regulation of cell proliferation, differentiation and apoptosis. We have investigated the relationship between Jun expression and cell death in the developing chicken inner
Cañón, Susana, Giráldez, Fernando, León, Yolanda, Sanz, Carmen, Varela-Nieto, Isabel, Álvarez, Luis   +5 more
core  

Targeting the MAPK Pathway in Brain Tumors: Mechanisms and Therapeutic Opportunities. [PDF]

Cancers (Basel)
Vrachas D, Kosma E, Giannopoulou AI, Margoni A, Gargalionis AN, El-Habr EA, Piperi C, Adamopoulos C.   +7 more
europepmc   +1 more source

Unraveling the Impact of KRAS Accessory Proteins on Oncogenic Signaling Pathways. [PDF]

Cells
Garg V, Hofmann RNHM, Saleem M, Mirzaiebadizi A, Hashemi GS, Hameed T, Jooyeh B, Pudewell S, Mehrabipour M, Mosaddeghzadeh N, Piekorz RP, Ahmadian MR.   +11 more
europepmc   +1 more source

Sirtuin 1 and Sirtuin 2 Gene Expressions in Colorectal Cancers. [PDF]

J Clin Pract Res
Düzenli T, Doğan D, Barışık NÖ.
europepmc   +1 more source

[Expression of Concern] MicroRNA‑195 targets VEGFR2 and has a tumor suppressive role in ACHN cells via PI3K/Akt and Raf/MEK/ERK signaling pathways. [PDF]

Int J Oncol
Sun P, Wang L, Lu Y, Liu Y, Li L, Yin L, Zhang C, Zhao W, Shen B, Xu W.   +9 more
europepmc   +1 more source

NX-1607: lifting the Cbl-b brake to promote T cell activation through MAPK/ERK pathways. [PDF]

J Immunother Cancer
To A, Sugimura R.
europepmc   +1 more source

Oncogenic B-Raf proto-oncogene, serine/threonine kinase-mediated hedgehog signalling in the pathogenesis and targeted therapy of melanoma. [PDF]

World J Clin Oncol
Rather RA.
europepmc   +1 more source