Results 1 to 10 of about 29,092 (95)

Armeniacae Semen Regulates Apoptosis and Cell Cycle Progression in MCF-7, MDA-MB-231, and T47D Breast Cancer Cell Lines [PDF]

Middle East Journal of Cancer, 2021
Background: Amygdalin is a glycoside ingredient of rosacea plants that exerts an antitumor effect by blocking the growth of the tumor cells. Therefore, we aimed to use the Armeniacae semen, a member of the Rosacea family, which contains a large amount of
Shiva Mosadegh Manshadi, Fatemeh Nadali, Mohammad Reza Shams Ardekani   +2 more
doaj   +1 more source

Expression of Bcl-2-family proteins in peripheral blood B-lymphocytes in patients with cronic lymphocytic leukemia [PDF]

Vojnosanitetski Pregled, 2004
Chronic lymphocytic leukemia (CLL) is a neoplastic disease characterized by the accumulation of morphologically mature monoclonal CD 5+ B cells in the early phase (G0/G1) of the cell cycle.
Brajušković Goran R., Vukosavić Slobodanka N., Dimitrijević Jovan, Cerović Snežana J., Ušaj-Knežević Slavica, Marjanović Slobodan A., Romac Stanka P., Milić-Škaro Anđelija   +7 more
doaj   +1 more source

Bcl-2 and Bax interaction in B-lymphocytes of peripheral blood in patients with chronic lymphocytic leukemia [PDF]

Vojnosanitetski Pregled, 2005
Background. Chronic lymphocytic leukemia (CLL) is a neoplastic disease characterized by the accumulation of morphologically mature monoclonal CD5+ B cells in the early phase (G0/G1) of the cell cycle.
Brajušković Goran R., Orolicki-Vukosavić Slobodanka, Cerović Snežana, Ušaj-Knežević Slavica, Marjanović Slobodan, Romac Stanka   +5 more
doaj   +1 more source

Adenoid cystic carcinoma: emerging role of translocations and gene fusions. [PDF]

, 2016
Adenoid cystic carcinoma (ACC), the second most common salivary gland malignancy, is notorious for poor prognosis, which reflects the propensity of ACC to progress to clinically advanced metastatic disease.
Brait, Mariana, Ha, Patrick K, Izumchenko, Evgeny, Meir, Juliet, Sidransky, David, Wysocki, Piotr T   +5 more
core   +5 more sources

Ubiquitylation in immune disorders and cancer: from molecular mechanisms to therapeutic implications [PDF]

, 2012
Conjugation of ubiquitin to proteins (ubiquitylation) has emerged to be one of the most crucial post-translational modifications controlling virtually all cellular processes.
Fulda, Simone, Rajalingam, Krishnaraj, Dikic, Ivan   +2 more
core   +2 more sources

The ansamycin antibiotic, rifamycin SV, inhibits BCL6 transcriptional repression and forms a complex with the BCL6-BTB/POZ domain [PDF]

, 2014
BCL6 is a transcriptional repressor that is over-expressed due to chromosomal translocations, or other abnormalities, in ~40% of diffuse large B-cell lymphoma.
A Melnick, A Shvarts, AA Alizadeh, AF Ghetu, AGW Leslie, AJ McCoy, AL Dent, Andrew G. Jamieson, Benjamin T. Goult, BH Ye, C Tunyaplin, CC Chang, CM Kunin, D Allman, DS Auld, EA Campbell, G Cattoretti, GD Barish, IS Lossos, J Oberoi, Javier Marcelo Di Noia, JM Polo, John W. R. Schwabe, K Offit, K Pervushin, KF Ahmad, L Cerchietti, L Pasqualucci, L Pasqualucci, LA Woods, LC Cerchietti, LC Cerchietti, Louise Fairall, MA Shipp, P Dhordain, P Dhordain, P Dhordain, P Emsley, Paul Ko Ferrigno, PR Evans, R Reljic, Robert Ford, S Duan, Sian E. Evans, Simon D. Wagner, WF Vranken, X Wang   +46 more
core   +8 more sources

Modulation of PKM alternative splicing by PTBP1 promotes gemcitabine resistance in pancreatic cancer cells [PDF]

, 2015
Pancreatic ductal adenocarcinoma (PDAC) is an aggressive and incurable disease. Poor prognosis is due to multiple reasons, including acquisition of resistance to gemcitabine, the first-line chemotherapeutic approach.
Bielli, P, Calabretta, S, Capurso, G, DELLE FAVE, Gianfranco, Fendrich, V, Passacantilli, I, Pilozzi, Emanuela, Sette, C.   +7 more
core   +4 more sources

Cell proliferation and apoptosis in gastric cancer and intestinal metaplasia Proliferação celular e apoptose em câncer gástrico e metaplasia intestinal

Arquivos de Gastroenterologia, 2005
BACKGROUND: Higher proliferation is commonly observed in cancer cells. Apoptosis can be a useful measure of a tumor cell kinetic. Alteration of the balance between proliferation and apoptosis is associated with cancer.
Nora Manoukian Forones, Ana Paula Souza Carvalho, Oswaldo Giannotti-Filho, Laércio Gomes Lourenço, Celina Tizuko Fujiyama Oshima   +4 more
doaj   +1 more source

Preferential expression of the transcription coactivator HTIF1alpha gene in acute myeloid leukemia and MDS-related AML [PDF]

, 2002
HTIF1α, a transcription coactivator which is able to mediate RARα activity and functionally interact with PML, is encoded by a gene on chromosome 7q32–34, which is a critical region in acute myeloid leukemias (AML). With the assumption that this gene may
AGUIARI, Gianluca, CASTOLDI, GL, CUNEO, Antonio, DE ANGELI, C, DEL SENNO, Laura, GANDINI, D, LANZA, F, MANZATI, E, PANDOLFI, PP   +8 more
core   +1 more source

Effect and mechanism of Juluo decoction combined with Ruhe powder in treatment of rat model of hyperplasia of mammary glands [PDF]

精准医学杂志
Objective To investigate the effect and mechanism of Juluo Decoction combined with Ruhe Powder in the treatment of rat model of hyperplasia of mammary glands.
NIE Weihong, LIU Hongxi, SUN Guoxin, LIU Chengcong, ZOU Xiao
doaj   +1 more source