Results 11 to 20 of about 60,057 (198)

Fas-induced Activation of the Cell Death-related Protease CPP32 Is Inhibited by Bcl-2 and by ICE Family Protease Inhibitors*

Journal of Biological Chemistry, 1996
The human proto-oncogene bcl-2 and its Caenorhabditis elegans homologue ced-9 inhibit programmed cell death. In contrast, members of the human interleukin-1β converting enzyme (ICE) family of cysteine proteases and their C.
R. Armstrong, Teresa Aja, J. Xiang, S. Gaur, J. Krebs, K. Hoang, X. Bai, S. Korsmeyer, D. Karanewsky, L. Fritz, K. Tomaselli   +10 more
semanticscholar   +1 more source

Dependence of protein-induced lipid bilayer deformations on protein shape [PDF]

, 2022
Membrane proteins typically deform the surrounding lipid bilayer membrane, which can play an important role in the function, regulation, and organization of membrane proteins. Membrane elasticity theory provides a beautiful description of protein-induced lipid bilayer deformations, in which all physical parameters can be directly determined from ...
arxiv   +1 more source

Multiple expression patterns of biopathological markers in primary invasive breast carcinoma: a useful tool for elucidating its biological behaviour.

Annals of Oncology, 1995
BACKGROUND Commonly used clinical and morphologic criteria have been reported to be of limited value in predicting the outcome of malignant tumours of the breast.
C. Ceccarelli, D. Santini, P. Chieco, M. Taffurelli, D. Marrano, A. Mancini   +5 more
semanticscholar   +1 more source

Sequential induction of NF-κB/Rel family proteins during B-cell terminal differentiation [PDF]

, 1994
The NF-kappa B/Rel family of at least five transcription factor polypeptides is thought to function both as a developmental regulator in B cells and as a rapid response system in all cells. To examine this notion in more detail, we determined the protein
Baltimore, David, Liou, Hsiou-Chi, Scott, Martin L., Sha, William C.   +3 more
core   +1 more source

Bcl-2 expression in rectal cancer Expressão da proteína bcl-2 no câncer de reto

Arquivos de Gastroenterologia, 2006
BACKGROUD: Proteins involved in apoptosis process seem to play an important role in colorectal carcinogenesis AIM: To determine the prevalence of bcl-2 protein immunohistochemical expression and its relation with clinical and histopathological variables ...
Paulo C. Contu, Simone S. Contu, Luis F. Moreira   +2 more
doaj   +1 more source

Binding of anisotropic curvature-inducing proteins onto membrane tubes [PDF]

Soft Matter 18, 3384-3394 (2022), 2022
Bin/Amphiphysin/Rvs superfamily proteins and other curvature-inducing proteins have anisotropic shapes and anisotropically bend biomembrane. Here, we report how the anisotropic proteins bind the membrane tube and are orientationally ordered using mean-field theory including an orientation-dependent excluded volume.
arxiv   +1 more source

Analysis of the immunohistochemical expressions of p53, bcl-2 and Ki-67 in colorectal adenocarcinoma and their correlations with the prognostic factors Análise das expressões imunoistoquímicas da p53, bcl-2 e Ki-67 no adenocarcinoma colorretal e suas correlações com os fatores prognósticos

Arquivos de Gastroenterologia, 2010
CONTEXT: Search of tumors markers that allow treatment with higher survival rates, and indicate the response to treatment and recurrence of cancer OBJECTIVE: To analyze the immunoexpression of the proteins p53, bcl-2 and Ki-67 in colorectal ...
Hunaldo Lima de Menezes, Mário Jorge Jucá, Edmundo Guilherme de A. Gomes, Benício L. Bulhões B. P. Nunes, Henrique Oliveira Costa, Delcio Matos   +5 more
doaj   +1 more source

Curvature sensing of curvature-inducing proteins with internal structure [PDF]

Phys. Rev. E 109, 024403 (2024), 2023
Many types of peripheral and transmembrane proteins can sense and generate membrane curvature. Laterally isotropic proteins and crescent proteins with twofold rotational symmetry, such as Bin/Amphiphysin/Rvs superfamily proteins, have been studied theoretically. However, proteins often have an asymmetric structure or a higher rotational symmetry.
arxiv   +1 more source

The Nefarious Nexus of Noncoding RNAs in Cancer [PDF]

, 2018
The past decade has witnessed enormous progress, which has seen the noncoding RNAs (ncRNAs) turn from the so called dark matter RNA to critical functional molecules, influencing most physiological processes in development and disease contexts.
Anastasiadou, Eleni, Faggioni, Alberto, J Slack, Frank, Trivedi, Pankaj   +3 more
core   +1 more source

Evaluation of Some Prognostic Biomarkers in Human Papillomavirus-Related Multiphenotypic Sinonasal Carcinoma [PDF]

Iranian Journal of Medical Sciences
Background: Human papillomavirus (HPV)-related multi phenotypic sinonasal carcinoma (HMSC) is a recently described tumor subtype with an unknown prognosis, often misdiagnosed with other sinonasal carcinomas, and associated with high-risk HPV (HR-HPV ...
Mohamed Ali Alabiad, Warda M. M. Said, Amal M. A. Adim, Mohammed Alorini, Amany Mohamed Shalaby, Walaa Samy, Shereen Elshorbagy, Doaa Mandour, Ibrahim Mohamed Saber, Amar Ibrahim Omar Yahia, Dina Ahmed Khairy   +10 more
doaj   +1 more source