Results 101 to 110 of about 21,686 (164)

Molecular Mechanisms and Clinical Divergences in HPV-Positive Cervical vs. Oropharyngeal Cancers: A Critical Narrative Review. [PDF]

open access: yesBMC Med
Martinelli C   +9 more
europepmc   +1 more source

Single-cell transcriptomics and epigenomics point to CD58-CD2 interaction in controlling primary melanoma growth and immunity. [PDF]

open access: yesCancer Commun (Lond)
Stubenvoll A   +16 more
europepmc   +1 more source

Transfection of Cardiac Muscle: Effects of Overexpression of c-myc and c-fos Proto-Oncogene Proteins in Primary Cultures of Neonatal Rat Cardiac Myocytes

open access: closedClinical Science, 1997
1. Studies of cells transfected with specific expression vectors allow functions of specific gene products to be investigated. We first established optimum conditions for transfection of neonatal cardiac myocytes in primary culture. Increased proto-oncogene expression has been implicated in the development of cardiac hypertrophy; we therefore wished to
Nicola K. Green   +4 more
semanticscholar   +4 more sources

Regulation of c-fos proto-oncogene expression by growth hormone: protein synthesis is not required for down-regulation.

open access: closedEndocrinology, 1993
Growth hormone (GH) has been previously shown in Ob1771 adipose cells to transiently stimulate the expression of the c-fos gene by a protein kinase C (PKC)-dependent pathway. This regulation takes place at a transcriptional level. In the presence of cycloheximide (CHX), stimulation by PKC activators or by serum leads to a "superinduction" of the c-fos ...
Sylvie Barcellini-Couget   +2 more
  +6 more sources

ACETALDEHYDE INDUCES C-FOS AND C-JUN PROTO-ONCOGENES IN FAT-STORING CELL CULTURES THROUGH PROTEIN KINASE C ACTIVATION

open access: closedAlcohol and Alcoholism, 1994
Hepatic fibrosis is an important morphological feature of alcohol-induced liver injury. We previously reported that acetaldehyde stimulates collagen I and fibronectin gene transcription in rat fat-storing cell (FSC) culture. We here evaluated whether acetaldehyde increases Col I and FN gene transcription through the induction of c-fos and c-jun proto ...
ALESSANDRO CASIN   +6 more
openalex   +5 more sources

Inhibition of proto-oncogene c-fos transcription by inhibitors of protein kinase C and ion transport

open access: closedEuropean Journal of Biochemistry, 1987
Both 4 beta-phorbol 12,13-didecanoate (PDD) and calcium ionophore A23187 induced c-fos mRNA accumulation with similar kinetics in human monocyte-like cells (U937). Their effects were additive. Cells pretreated with PDD were not induced to accumulate c-fos mRNA by PDD but remained responsive to the induction by A23187.
Motoko Shibanuma   +2 more
openalex   +4 more sources

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