Sirtuin 2 exacerbates renal tubule injury and inflammation in diabetic mice via deacetylation of c-Jun/c-Fos. [PDF]
Chen L+6 more
europepmc +1 more source
Casticin Inhibits Osteoclastogenesis via NF-κB/BCL-2 Signaling Pathway. [PDF]
Huang A, Gu Z, Jin J, Nie T.
europepmc +1 more source
Maternal Melatonin Contributes to Offspring Hair Follicle Development Through Transcriptional Regulation of the AP-1 Complex and MAPK Pathway. [PDF]
Feng Y+8 more
europepmc +1 more source
Molecular characterization of PANoptosis-related genes in chronic kidney disease. [PDF]
Zhang WT+5 more
europepmc +1 more source
Molecular Mechanisms and Clinical Divergences in HPV-Positive Cervical vs. Oropharyngeal Cancers: A Critical Narrative Review. [PDF]
Martinelli C+9 more
europepmc +1 more source
Single-cell transcriptomics and epigenomics point to CD58-CD2 interaction in controlling primary melanoma growth and immunity. [PDF]
Stubenvoll A+16 more
europepmc +1 more source
1. Studies of cells transfected with specific expression vectors allow functions of specific gene products to be investigated. We first established optimum conditions for transfection of neonatal cardiac myocytes in primary culture. Increased proto-oncogene expression has been implicated in the development of cardiac hypertrophy; we therefore wished to
Nicola K. Green+4 more
semanticscholar +4 more sources
Growth hormone (GH) has been previously shown in Ob1771 adipose cells to transiently stimulate the expression of the c-fos gene by a protein kinase C (PKC)-dependent pathway. This regulation takes place at a transcriptional level. In the presence of cycloheximide (CHX), stimulation by PKC activators or by serum leads to a "superinduction" of the c-fos ...
Sylvie Barcellini-Couget+2 more
+6 more sources
Hepatic fibrosis is an important morphological feature of alcohol-induced liver injury. We previously reported that acetaldehyde stimulates collagen I and fibronectin gene transcription in rat fat-storing cell (FSC) culture. We here evaluated whether acetaldehyde increases Col I and FN gene transcription through the induction of c-fos and c-jun proto ...
ALESSANDRO CASIN+6 more
openalex +5 more sources
Inhibition of proto-oncogene c-fos transcription by inhibitors of protein kinase C and ion transport
Both 4 beta-phorbol 12,13-didecanoate (PDD) and calcium ionophore A23187 induced c-fos mRNA accumulation with similar kinetics in human monocyte-like cells (U937). Their effects were additive. Cells pretreated with PDD were not induced to accumulate c-fos mRNA by PDD but remained responsive to the induction by A23187.
Motoko Shibanuma+2 more
openalex +4 more sources