Results 1 to 10 of about 207,584 (200)
Expression and Function of the c-kit Proto-Oncogene Protein in Mouse Sperm1 [PDF]
Biology of Reproduction, 1997 Huailiang Feng +2 more
openaire +2 more sources
No detection of c-kit gene mutations in exons 9, 11, 13 and 17 and low CD117 expression in plaque-stage mycosis fungoides [PDF]
Anais Brasileiros de Dermatologia, 2018 : The growth factor receptor c-kit (CD117) is expressed in immature T-cells and in some advanced forms of mycosis fungoides. c-kit gene mutation results in unrestricted neoplastic proliferation.
David Aldo De Luca +3 more
doaj +1 more source
Evaluation of the relationship between c-Kit expression and mean platelet volume in classic Kaposi's sarcoma [PDF]
Anais Brasileiros de Dermatologia, 2016 : Background: c-Kit is a proto-oncogene that encodes tyrosine kinase receptor (CD117). Mean platelet volume (MPV) is a useful marker, providing information on platelet function and diameter.
Ibrahim Sehitoglu +5 more
doaj +1 more source
Cancers, 2022 Simple Summary Galectins are a family of β-galactoside binding proteins whose levels are altered in various stages of different types of cancer. This study provides an analytical comparison of 50 frequently mutated genes in two common cancers and the ...
Avery T. Funkhouser +9 more
semanticscholar +1 more source
Open Medicine, 2023 Ubiquitin-conjugating enzyme E2 C (UBE2C) plays a carcinogenic role in gastric cancer (GC); yet, its role in cisplatin (DDP) resistance in GC is enigmatic.
Long Jiegen +7 more
doaj +1 more source
Prospects of Chemotherapy for Gastrointestential Stromal Colon Tumours
Креативная хирургия и онкология, 2020 Gastrointetinal stromal tumours are the most common primary mesenchymal tumours of the gastrointestinal tract. According to statistical data, the annual incidence of this pathology in Russia comprises 13 patients per 1 million inhabitants, i.e.
A. R. Mukhamediyarov +3 more
doaj +1 more source
Review papers The role of KIT gene mutations in pathogenesis of pediatric mastocytosis
Przegląd Dermatologiczny, 2015 Mastocytosis is characterized by excessive proliferation and accumulation of mast cells in skin and/or other organs. Two forms of the disease, cutaneous and systemic mastocytosis, differ significantly in symptomatology and clinical course.
Joanna Dawicka +5 more
doaj +1 more source
G-Quadruplex loops regulate PARP-1 enzymatic activation
Nucleic Acids Research, 2020 G-Quadruplexes are non-B form DNA structures present at regulatory regions in the genome, such as promoters of proto-oncogenes and telomeres. The prominence in such sites suggests G-quadruplexes serve an important regulatory role in the cell.
Andrea D Edwards +4 more
semanticscholar +1 more source
Characterization of the Promoter Region of the Human c‐kit Proto‐oncogene
Japanese journal of cancer research : Gann, 1993 The c‐kit proto‐oncogene encodes a tyrosine kinase receptor for stem cell factor and plays a critical role in the growth and differentiation of various types of cells including hematopoietic stem cells.
Katsuya Yamamoto +3 more
semanticscholar +1 more source
Sterile α-motif domain requirement for cellular signaling and survival
Journal of Biological Chemistry, 2020 Hundreds of sterile α-motif (SAM) domains have predicted structural similarities and are reported to bind proteins, lipids, or RNAs. However, the majority of these domains have not been analyzed functionally. Previously, we demonstrated that a SAM domain-
Suhita Ray +5 more
semanticscholar +1 more source