Results 81 to 90 of about 19,940,452 (132)

Hepatitis B virus X protein induces E6-associated protein-mediated proteasomal degradation of p53 phosphorylated at Ser-15. [PDF]

J Gen Virol
Han J, Kwon Y, Park JM, Jang KL.
europepmc   +1 more source

The Role of Alternative Splicing in Lung Cancer: Mechanisms, Regulators, and Therapeutic Implications. [PDF]

Int J Mol Sci
Shang L, Wang N, Liu Q, Chen L, Liu H.
europepmc   +1 more source

E3 Ubiquitin Ligase MDM2 Promotes Growth and CD8⁺ T Cell Dysfunction in Gastric Cancer Through Degradation of SST. [PDF]

J Gastroenterol Hepatol
Yang F, Zhang X, Ji J, Li S, Fang X, Yang L, Guo X.   +6 more
europepmc   +1 more source

Therapeutic Targets for Overcoming BCR::ABL1 Tyrosine Kinase Inhibitor Resistance in Chronic Myeloid Leukemia. [PDF]

Oncol Res
Tsubaki M, Matsuo T, Komori R.
europepmc   +1 more source

Harnessing MDM2-Mediated Targeted Degradation of Transcriptional and Epigenetic Machinery to Disrupt Oncogenic Addictions in Pediatric Sarcoma. [PDF]

Adv Sci (Weinh)
Zhou J, Guan X, Li N, Zhang Y, Xie L, Huang X, Zhu Z, Ren Z, Yu X, Guo H, Wu Y, Ma L, Zheng S, Zhang J, Liu J, Lee VK, Chen W, Koeffler HP, Wang J, Han X, Chen Y, Xu L.   +21 more
europepmc   +1 more source

Apoptosis of Mdm2-deficient osteocytes enhances osteogenesis through TRPM8-enriched apoptotic vesicles. [PDF]

Bone Res
Liu X, Zheng H, Wang A, Liu J, Chen Z, Chen Y, Yang G, Chen D, Zhang Y, Yuan G.   +9 more
europepmc   +1 more source

Hypoxia-Inducible Factor-1α Stabilization Alleviates Hypoxia-Induced Temporomandibular Joint Osteoarthritis by Activating MDM2 to Suppression of p53 Signalling. [PDF]

Int Dent J
Chen Z, Cai J, Cai J, Yang X, Wang Z, Chen L, Chen S, Xu L, Wang H.   +8 more
europepmc   +1 more source

Elucidating the Mechanisms of Trichloroethylene-Induced Kidney Cancer: Network Toxicology, Molecular Docking, and In Vitro Validation. [PDF]

J Biochem Mol Toxicol
Ma W, Cai H.
europepmc   +1 more source

HIF1α mediates resistance to radiation and to KRAS inhibitors in pancreatic adenocarcinoma. [PDF]

PLoS One
Tu KJ, Roy SK, Kingsbury TJ, Shukla HD.
europepmc   +1 more source

Ginkgetin enhances the antitumor effect of Taxol on human breast cancer MCF-7 cells via ferroptosis mediated by the MDM2-p53-YAP1 axis. [PDF]

Sci Rep
Li G, Yan W, Peng X, Yin Z, Mahati S.
europepmc   +1 more source