GTPBP4 promotes colorectal cancer cell proliferation by positively regulating MYC-driven glycolytic metabolism. [PDF]
Zhao K +5 more
europepmc +1 more source
Tumorigenicity of SEWA murine tumor cells correlates with degree of c-myc amplification
Previous studies have shown that cells of the SEWA mouse tumor contain amplified copies of the proto-oncogene c-myc in the aberrant chromosomal structures of double minutes (DMs), homogeneously staining regions (HSRs) and C-bandless chromosomes (CMs ...
Schwab, M et al +5 more
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3D chromatin architecture in cancer: mechanisms of dysregulation and emerging therapeutic strategies. [PDF]
Jang S, Yoo KH.
europepmc +1 more source
Functional siRNA Screen Links Ras/MAPK and Wnt Pathway to EV Secretion in HCT-116 Colorectal Cancer Cells. [PDF]
Pätzold SM, Gross JC.
europepmc +1 more source
Overexpression of Cyclin D1 and C-Myc Gene Products in Human Primary Epithelial Ovarian Cancer
Cyclin D1 and c-Myc are key participants in the cell-cycle pathway, in which aberrancies have been associated with malignant transformation. To date, data on the relationship of expression of these proteins and histologic subtype of epithelial ovarian ...
周松男 +1 more
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Molecular Mechanisms of Diffuse Large B-Cell Lymphoma and the Complexities of Tumor Development. [PDF]
Alzahrani WI.
europepmc +1 more source
KRAS and MYC synergistic inhibition: a powerful strategy targeting KRAS-mutant cancers. [PDF]
Yan M +5 more
europepmc +1 more source
Nucleic Acid Therapeutics for "Undruggable" Cancer Targets: Mechanisms, Challenges, and Prospects. [PDF]
Xu F +6 more
europepmc +1 more source
Pilot study: transduction of primary paraganglioma chromaffin tumour cells with inducible c-MYC drives cell proliferation. [PDF]
Zhang J +6 more
europepmc +1 more source
A large body of evidence has been accumulated that demonstrates dominant effects of Myc proto-oncoproteins on different aspects of cellular growth, Myc is one of the few proteins that is sufficient to drive resting cells into the cell cycle and promote ...
Larsson, LG,, Luscher, B,
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