G-quadruplexes: Kinetic stability and effects on the c-KIT promoter
In addition to the famous Watson & Crick model for B-form duplex DNA, guanine-rich DNA sequences can self-assemble under certain conditions to form a four-stranded structure known as a G-quadruplex. G-quadruplexes are composed of stacks of Gquartets,
Raouf, Tara
core +1 more source
Transcription-responsive regulation of c-myc proto-oncogene – structural and biophysical studies [PDF]
The Far-UpStream Element (FUSE) regulatory system tightly controls the expression of c-myc proto-oncogene – a master regulator of cellular proliferation and differentiation.
Cukier, C.D.
core
Proteomic Identification of the MYST Domain Histone Acetyltransferase TIP60 as a Coactivator of the Myeloid Transcription Factor C/EBPα [PDF]
The transcription factor C/EBPα is a key player in granulopoiesis and leukemogenesis. In the present study, we sought to identify C/EBPα interacting proteins.
Bararia, Deepak
core +1 more source
Expression of proto-oncogene c-Myc in patients with urinary bladder transitional cell carcinoma
Background: C-Myc is a proto-oncogene located on human chromosome 8. It encodes a transcriptional factor which regulates the expression of approximately 10% to 15% of human genes, playing a crucial role in cell growth, differentiation, cellular ...
Fragkoulis, C. +7 more
core
The preimplantation mammalian embryo is sensitive to the environment in which they develop and grow, either in vivo or in vitro. Disturbance to embryo environmental conditions can affect embryo growth.
Bakheet, Ayat
core +1 more source
Negative regulation of c-myc transcription involves myc family proteins.
Expression of the c-myc gene is suppressed in NIH 3T3 mouse fibroblast cells infected with recombinant retroviruses expressing high levels of v-myc (10-fold greater than those of c-myc).
Huleihel, M +6 more
core
The study aims to evaluate the cause of cervical cancer in a cohort of patients and to establish whether or not human papillomavirus (HPV) is the leading risk factor and to determine whether or not c-myc oncogene over-expression is a predicative marker ...
Greenwell, P. +3 more
core
Eliminate <i>Mycobacterium tuberculosis</i> via HELZ2 and up-regulating ATG16L1 to promote macrophage autophagy. [PDF]
Wang T, Liu L, Lei Y.
europepmc +1 more source
lncRNA ch-MYC-AS1 restricts ALV-J replication by disrupting the ANXA2-C-Myc oncogenic axis. [PDF]
Fan S +8 more
europepmc +1 more source
The v- and c-myc oncogene proteins colocalize in situ with small nuclear ribonucleoprotein particles
The intranuclear distribution of the v-myc and c-myc oncogene proteins were studied by immunofluorescence and immunoelectron microscopy. The nuclear distribution pattern of these proteins is shown to be identical to the distribution of small nuclear ...
Spector, D. L. +2 more
core

