Results 41 to 50 of about 17,080,419 (148)

PATTERNFINDER: combined analysis of DNA regulatory sequences and double-helix stability

BMC Bioinformatics, 2004
Background Regulatory regions that function in DNA replication and gene transcription contain specific sequences that bind proteins as well as less-specific sequences in which the double helix is often easy to unwind.
Huang Yanlin, Kowalski David
doaj   +1 more source

Transcriptional regulation of the human c-myc gene [PDF]

, 1988
The involvement of c-myc in the genesis of animal neoplasia is now well documented for several systems. In order to define the precise role played by the myc gene in tumorigenesis, a better understanding of the normal regulation of myc expression is ...
Wilkie, N M, Whitelaw, B, Lang, J C, Talbot, S   +3 more
core  

Pituitary tumor-transforming gene expression is a prognostic marker for tumor recurrence in squamous cell carcinoma of the head and neck [PDF]

, 2006
Background The proto-oncogene pituitary tumor-transforming gene (PTTG) has been shown to be abundantly overexpressed in a large variety of neoplasms likely promoting neo-vascularization and tumor invasiveness.
Solbach, Christine, Peters Silke, Eckerdt, Frank, Peters, Silke, Knecht, Rainald, Roller, Marc, Roller Marc, Eckerdt Frank, Solbach Christine, Knecht Rainald   +9 more
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Interleukin-1/toll-like receptor-induced nuclear factor kappa B signaling participates in intima hyperplasia after carotid artery balloon injury in goto-kakizaki rats: a potential target therapy pathway.

PLoS ONE, 2014
The value of restenosis after percutaneous coronary intervention (PCI) is recognized worldwide, especially for diabetic patients. Interleukin-1/Toll-like receptor (IL-1/TLR) signaling is involved in innate and adaptive immune responses, but whether and ...
Xiaotian Zhang, Yi Wang, Wenjing Hu, Dongye Li, Zhongmin Zhou, Defeng Pan, Wanling Wu, Tongda Xu   +7 more
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Enhanced transcription of c-myc proto-oncogene in spleen lymphocytes from lupus-prone mice during the growing process [PDF]

, 1989
The expression of c-myc proto-oncogene in spleen lymphocytes has been studied in lupus-prone mice (MRL/Mp-lpr/lpr), an animal model for the human autoimmune disease systemic lupus erythematosus, during the growing process, in comparison to control mice ...
Yasuhiro Deguchi, Deguchi, Yasuhiro, Kishimoto, Susumu, Susumu Kishimoto   +3 more
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Design, Synthesis, and Anti-Leukemic Evaluation of a Series of Dianilinopyrimidines by Regulating the Ras/Raf/MEK/ERK and STAT3/c-Myc Pathways

Molecules
Although the long-term survival rate for leukemia has made significant progress over the years with the development of chemotherapeutics, patients still suffer from relapse, leading to an unsatisfactory outcome.
Chaoyan Wang, Bo Wang, Yu Mou, Xiang Liu, Qiqing Chen, Weidong Pu, Qing Rao, Chunlin Wang, Jingrui Song, Yubing Huang, Longjia Yan, Lei Huang, Yanmei Li   +12 more
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Stem cell regulation: conserved pluripotency, transcriptional, and metabolic networks in animals and plants

Frontiers in Cell and Developmental Biology
Animal and plant stem cells have evolved lineage-specific regulatory networks over billions of years of independent evolution. However, their shared unicellular origin implies the preservation of shared ancestral regulatory modules and the repeated use ...
Qiang Huang, Qi-Sheng Tang, Ming-Yue Qi, Xiao-Yu Yang, Hong-Qing Xie, Hui Guo, Hui Guo, Xin-Yu Zhang   +7 more
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Wnt/beta-catenin/Tcf signaling: A critical pathway in gastrointestinal tumorigenesis [PDF]

, 2002
Cancers of the gastrointestinal tract, including the liver, bile ducts, and pancreas, constitute the largest group of malignant tumors. Colorectal cancer is one of the most common neoplastic diseases in Western countries and one of the leading causes of ...
Bommer, G., Göke, Burkhard, Göke, B., Kolligs, Frank T, Bommer, Guido, Kolligs, F. T.   +5 more
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A biologia molecular no prognóstico do carcinoma da tireóide

Revista do Colégio Brasileiro de Cirurgiões
This overview examines some selected genetic mechanisms of cancer development. Strong evidence has been accumulated suggesting that alteration in either the struture or activity of proto-oncogene contributes to the development and for the maintenance of ...
Aluizio Soares de Souza Rodrigues
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Direct Regulation of Hsp60 Expression by C-Myc Induces Transformation

, 2009
The c-MYC proto-oncogene encodes a ubiquitous transcription factor involved in cell proliferation and tumorigenesis. Heat shock protein 60 ( HSP60) plays an essential role in assisting many newly synthesized proteins to reach their native forms ...
鄧述諄;吳國瑞, TENG, SHU-CHUN;WU, KOU-JUEY;WU, KOU- JUEY   +1 more
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