Results 101 to 110 of about 1,022,619 (266)

MRI Space Mission: A Stepwise Paediatric MRI Training Protocol for Young Children

open access: yes, 2021
The MRI Space Mission is a child-centred, stepwise paediatric MRI training protocol for young children. The protocol consists of a series of mini-activities that are designed to familiarize young children with the MRI scanner and scanning procedures ...
Wu, Chiao-Yi   +7 more
core   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Preparation and Characterization of IL-22 mRNA-loaded Lipid Nanoparticles

open access: yes, 2023
Interleukin-22 (IL-22) has been demonstrated as a critical regulator of epithelial homeostasis and repair; it showed an anti-inflammatory effect against ulcerative colitis.
Merlin, Didier   +6 more
core   +1 more source

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

open access: yesFEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai   +9 more
wiley   +1 more source

Tau acetylation at K331 has limited impact on tau pathology in vivo

open access: yesFEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto   +3 more
wiley   +1 more source

An efficient and private RFID authentication protocol supporting ownership transfer [PDF]

open access: yes, 2013
Radio Frequency IDentification (RFID) systems are getting pervasively deployed in many daily life applications. But this increased usage of RFID systems brings some serious problems together, security and privacy. In some applications, ownership transfer
Arslan, Atakan   +7 more
core   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

open access: yesFEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa   +5 more
wiley   +1 more source

The efficacy of silver needle therapy for treating low back pain: a protocol for meta-analysis of randomized controlled trials

open access: yesFrontiers in Medicine
BackgroundAs population aging and unhealthy living habits may exacerbate the prevalence and burden of low back pain (LBP), effective treatment and improvement of patient quality of life are particularly critical.
Wangyu Li, Xueru Xu, Rongguo Liu
doaj   +1 more source

DynCNET: a negotiation and coordination protocol for dynamic task assignment. [PDF]

open access: yes
Task assignment in Multi-Agent Systems is a complex coordination problem, especially in systems that operate under dynamic and changing conditions. Adaptive task assignment is used to handle these dynamic and changing circumstances.
Weyns, Danny   +3 more
core  

Equity and the Kyoto Protocol [PDF]

open access: yes, 2007
Global climate change raises a number of important issues for political scientists and theorists. One issue concerns the ethics of implementing policies that seek to manage the threats associated with dangerous climate change in order to protect the ...
Page, Edward
core   +1 more source

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