Results 111 to 120 of about 4,819,126 (312)
Jingnan Jia, Chaoqun Yan, Xiancheng Zheng, Anqi Shi, Zhijun Li, Lufan Xu, Zhiyuan Hui, Yichao Chen, Zimin Cao, Jun Wang Dongzhimen Hospital, Beijing University of Chinese Medicine, Beijing, People’s Republic of ChinaCorrespondence: Chaoqun Yan; Jun Wang,
Jia J +9 more
doaj
An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes
GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg +14 more
wiley +1 more source
The development and implementation of a radiation therapy bariatric protocol
The rate of obesity is increasing in the Australian population, and this also includes patients with cancer. The safety and dignity of this cohort of patients is paramount as well as the timely acquisition of equipment required to assist patients with ...
Stacey Cooke +5 more
doaj +1 more source
BackgroundGeneralized anxiety disorder (GAD) is a prevalent mental disorder characterized by excessive tension, worry, fear, and autonomic symptoms, which brings huge suffering to patients.
Wang Yao +6 more
doaj +1 more source
Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics
Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt +8 more
wiley +1 more source
A Systematic Literature Review Protocol to understand the Healthcare Service Innovation Ecosystem
The research's primary goal is to address the innovation ecosystem in healthcare services to understand how interaction among stakeholders occurs and how that interaction influences or does not influence the results obtained from the innovation process ...
Rosa Milena Gomez-Caballero +2 more
doaj +1 more source
Liver organoids: modelling complexity in homeostasis and disease
Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley +1 more source
Efficient Transport Protocol for Networked Haptics Applications [PDF]
The performance of haptic application is highly sensitive to communication delays and losses of data. It implies several constraints in developing networked haptic applications.
Wirz, Raul +5 more
core
Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network
Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley +1 more source

