Results 101 to 110 of about 2,462,286 (267)
Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations
FEBS Letters, EarlyView.The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas +6 more
wiley +1 more source
Molecular Oncology, EarlyView.Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat +8 more
wiley +1 more source
Migration trends and outlook: 2013/2014 [PDF]
, 2015 This report examines trends in temporary and permanent migration to and from New Zealand. The report updates trends to 2013/14 and compares recent immigration patterns with patterns identified in previous years.
Innovation and Employment (New Zealand) +1 more
core
Molecular Oncology, EarlyView.In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge +17 more
wiley +1 more source
F-HB+: A Scalable Authentication Protocol for Low-Cost RFID Systems
, 2011 Non
Maire O\u27Neill +4 more
core +1 more source
Subtype‐specific enhancer RNAs define transcriptional regulators and prognosis in breast cancers
Molecular Oncology, EarlyView.This study employed machine learning methodologies to perform the subtype‐specific classification of RNA‐seq data sets, which are mapped on enhancers from TCGA‐derived breast cancer patients. Their integration with gene expression (referred to as ProxCReAM eRNAs) and chromatin accessibility profiles has the potential to identify lineage‐specific and ...
Aamena Y. Patel +6 more
wiley +1 more source
RV Ronald H. Brown Cruise RB0701, 21 Mar-10 Apr 2007. RAPID mooring cruise report [PDF]
, 2008 This report describes the mooring operations conducted during RV Ronald H. Brown Cruise RB0701 conductedbetween 21 March 2007 and 10 April 2007.These mooring operations were completed as part of the United Kingdom Natural Environment Research Council ...
Baringer, M.O., Kanzow, T.
core
Molecular Oncology, EarlyView.Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano +6 more
wiley +1 more source
COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells
Molecular Oncology, EarlyView.This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos +6 more
wiley +1 more source
Revista Brasileira de Saúde e Produção Animal, 2011 Objetivou-se com este estudo avaliar a influência da associação de duas doses contínuas da Somatotropina Recombinante Bovina (rbST) a um protocolo de superovulação sobre a quantidade e a qualidade dos embriões produzidos, além da taxa de gestação de ...
Bruno Henrique Araújo Andrade +7 more
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