Results 111 to 120 of about 2,462,286 (267)
A luteal estradiol protocol for expected poor-responders improves embryo number and quality.
, 2008 OBJECTIVE: To compare embryo and oocyte data between a standard protocol and a luteal phase estradiol protocol. DESIGN: Retrospective paired cohort analysis. SETTING: Private in vitro fertilization (IVF) center.
Hill, Micah J +5 more
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Efficient route discovery for reactive routing [PDF]
, 2013 This thesis was submitted for the degree of Doctor of Philosophy and awarded by Brunel University.Information on the location of mobile nodes in Mobile Ad-hoc Networks (MANETs) has the potential to significantly improve network performance.
Hamad, Sofian
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Molecular Oncology, EarlyView.Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau +36 more
wiley +1 more source
Negotiating the Nagoya Protocol: Indigenous Demands for Justice
, 2014 On October 29, 2010, following two weeks of intense negotiations, parties to the Convention on Biological Diversity (CBD) at the Tenth Conference of Parties (COP10) in Nagoya, Japan, adopted the Nagoya Protocol on Access to Genetic Resources and the Fair
Kimberly R. Marion Suiseeya
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Molecular Oncology, EarlyView.Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang +12 more
wiley +1 more source
Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer
Molecular Oncology, EarlyView.COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann +61 more
wiley +1 more source
Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma
Molecular Oncology, EarlyView.The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic +5 more
wiley +1 more source
Molecular Oncology, EarlyView.Targeted therapy was evaluated in SHH medulloblastoma using neuroepithelial stem cell (NES) and tumor‐derived NES‐like (tNES) models in 2D monolayers and 3D spheroids. PI3K, AKT, and CDK4/6 inhibitors had minimal effects in NES but markedly reduced viability and growth and induced apoptosis in tNES cells, revealing distinct therapeutic vulnerabilities.
Monika Lukoseviciute +4 more
wiley +1 more source
The role of genomic Copy Number Variation (CNV) in osteoporosis
, 2012 Copy number variation (CNV) is a relatively novel source of genetic variation, involving the duplication or deletion of segments of genomic DNA (gDNA) sequence, thereby changing the original number of DNA copies.
Connolly, Kate
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Comparing test sets and criteria in the presence of test hypotheses and fault domains
, 2002 A number of authors have considered the problem of comparing test sets and criteria. Ideally test sets are compared using a preorder with the property that test set T1 is at least as strong as T2 if whenever T2 determines that an implementation p is ...
Hierons, RM
core +1 more source